A nomogram model based on MRI and radiomic features developed and validated for the evaluation of lymph node metastasis in patients with rectal cancer.
Purpose: The aim of this study was to develop and validate a nomogram model to evaluate lymph node metastasis (LNM) in patients with rectal cancer (RC). Methods: A total of 162 patients with RC were included in the study. The MRI reported model, the Radscore model, and the Complex model were constru...
| Publicado en: | Abdominal Radiology Vol. 47; no. 12; pp. 4103 - 4115 |
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| Autores principales: | , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Dec2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=160002345&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 160002345 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 2366004X JT14 jtl: Abdominal Radiology issn: 2366004X maglogo: N pubinfo: dt: Dec2022 vid: 47 iid: 12 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 160002345 159099352 10.1007/s00261-022-03672-5 160002345 ppf: 4103 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: A nomogram model based on MRI and radiomic features developed and validated for the evaluation of lymph node metastasis in patients with rectal cancer. aug: au: Su, Yexin Zhao, Hongyue Liu, Pengfei Zhang, Linhan Jiao, Yuying Xu, Peng Lyu, Zhehao Fu, Peng affil: Department of Magnetic Resonance, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China sug: ab: Purpose: The aim of this study was to develop and validate a nomogram model to evaluate lymph node metastasis (LNM) in patients with rectal cancer (RC). Methods: A total of 162 patients with RC were included in the study. The MRI reported model, the Radscore model, and the Complex model were constructed using the logistics regression (LR) algorithm. The DeLong test and decision curve analysis (DCA) were used to compare the prediction performance and clinical utility of these models. The nomogram model was constructed to visualize the prediction results of the best model. Model performance was evaluated in the training and validation groups, and the calibration curve and Hosmer–Lemeshow goodness of fit test were used to evaluate the calibration. Result: All three models constructed by the LR algorithm were good at identifying LNM. The DeLong test and the DCA results showed that the Complex model outperformed the MRI reported model and the Radscore model in relation to their predictive performance and clinical utility. The nomogram of the Complex model had an area under the curve (AUC) of 0.902 (95% confidence interval (CI) 0.848–0.957) in the training group and an AUC of 0.891 (95% CI 0.799–0.983) in the validation group. Meanwhile, the nomogram showed good calibration. Conclusion: The nomogram model constructed based on T2WI radiomics and MRI reported had good diagnostic efficacies for LNM in patients with RC, and provided a new auxiliary method for accurate and individualized clinical management. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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