Postoperative quality of life and therapy-related impairments of oral cancer in relation to time-distance since treatment.

Purpose: Oral cancer resection can cause physical and psychological impairments that influence the quality of life (QoL). Depending on the postoperative time-distance, the occurrence and intensity of these impairments may change. We evaluated the sequelae and changes in therapy-related impairments d...

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Publicado en:Journal of Cancer Survivorship Vol. 16; no. 6; pp. 1366 - 1379
Autores principales: Jehn, Philipp, Spalthoff, Simon, Lentge, Fritjof, Zeller, Alexander-Nicolai, Tavassol, Frank, Neuhaus, Michael-Tobias, Eckstein, Fabian Matthias, Krüskemper, Gertrud, Gellrich, Nils-Claudius, Korn, Philippe
Formato: research Journal Article
Publicado: Springer Nature Dec2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2022
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s11764-021-01118-3
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        atl: Postoperative quality of life and therapy-related impairments of oral cancer in relation to time-distance since treatment.
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          Jehn, Philipp
          Spalthoff, Simon
          Lentge, Fritjof
          Zeller, Alexander-Nicolai
          Tavassol, Frank
          Neuhaus, Michael-Tobias
          Eckstein, Fabian Matthias
          Krüskemper, Gertrud
          Gellrich, Nils-Claudius
          Korn, Philippe
        affil: Department of Oral and Maxillofacial Surgery, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany
      sug:
        subj:
          Mouth Neoplasms Surgery
          Carcinoma, Squamous Cell Surgery
          Carcinoma, Squamous Cell Pathology
          Mouth Neoplasms Pathology
          Retrospective Design
          Human
          Quality of Life Psychosocial Factors
          Neoplasm Recurrence, Local
          Comparative Studies
          Multicenter Studies
          Evaluation Research
          Validation Studies
          Ferrans and Powers Quality of Life Index
          Questionnaires
      ab: Purpose: Oral cancer resection can cause physical and psychological impairments that influence the quality of life (QoL). Depending on the postoperative time-distance, the occurrence and intensity of these impairments may change. We evaluated the sequelae and changes in therapy-related impairments during the postoperative course to detect associations between the time since surgery and the presence of disorders.Methods: Data from a questionnaire completed by 1359 patients who underwent surgical treatment of oral squamous cell carcinoma and were involved in a multicenter rehabilitation study of the German-Austrian-Swiss Cooperative Group on Tumors of the Maxillofacial Region (DÖSAK) that included 43 oral and maxillofacial clinics in Germany, Austria, and Switzerland were retrospectively analyzed.Results: Physical impairments, including those in appearance, mouth opening ability, ability to smell, gastric disorders, mandible mobility, breathing, and shoulder/arm mobility, were significantly associated with and increased with time-distance since surgery. Esthetic appearance most strongly correlated with the highest perception of worsening. Regarding psychological disorders, worry about tumor recurrence, depression, and worse prospects were significantly associated. Among the postoperative sequelae, fear of tumor recurrence decreased continuously; however, depression and worse prospects increased. The general QoL did not significantly differ overall during the postoperative course.Conclusions: Therapy-related impairments change during the postoperative course based on the time-distance since surgery. The general QoL may not markedly vary; however, single impairments, to some extent, can increase or decrease.Implications For Cancer Survivors: Continuous adaptation of supportive cancer therapy is required during follow-up to sufficiently address individual treatment needs.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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