Evaluation of drug interactions of saxagliptin with sildenafil in healthy volunteers.

Purpose: The purpose of this study is to investigate the effect of sildenafil a CYP3A4 substrate and inhibitor on the pharmacokinetics and safety of saxagliptin. Methods: Eighteen healthy volunteers were recruited in sequential; single-center study to determine pharmacokinetic parameters of saxaglip...

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Publicado en:European Journal of Clinical Pharmacology Vol. 78; no. 12; pp. 1935 - 1945
Autores principales: Mansour, Rania Y., ElBorolossy, Radwa, Shaheen, Sara M., Sabri, Nagwa A.
Formato: research tables/charts Journal Article
Publicado: Springer Nature Dec2022
Acceso en línea:Ver este registro en EBSCOhost