Preferences Across Pre-Exposure Prophylaxis Modalities Among Young Men Who Have Sex with Men in the United States: A Latent Class Analysis Study.

Access to daily oral pre-exposure prophylaxis (PrEP) is suboptimal among young cisgender men who have sex with men (YMSM) in the United States. Next-generation modalities that do not involve daily oral regimens may mitigate some of the barriers to PrEP use. We identified latent classes of YMSM based...

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Publicado en:AIDS Patient Care & STDs Vol. 36; no. 11; pp. 431 - 443
Autores principales: Valente, Pablo K., Bauermeister, José A., Lin, Willey Y., Silva, Daniel Teixeira Da, Hightow-Weidman, Lisa, Drab, Ryan, Mayer, Kenneth H., Operario, Don, Rusley, Jack, Biello, Katie B.
Formato: research tables/charts Journal Article
Publicado: Mary Ann Liebert, Inc. Nov2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2022
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      pub: Mary Ann Liebert, Inc.
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        10.1089/apc.2022.0111
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        atl: Preferences Across Pre-Exposure Prophylaxis Modalities Among Young Men Who Have Sex with Men in the United States: A Latent Class Analysis Study.
      aug:
        au:
          Valente, Pablo K.
          Bauermeister, José A.
          Lin, Willey Y.
          Silva, Daniel Teixeira Da
          Hightow-Weidman, Lisa
          Drab, Ryan
          Mayer, Kenneth H.
          Operario, Don
          Rusley, Jack
          Biello, Katie B.
        affil: School of Public Health, Brown University, Providence, Rhode Island, USA.
      sug:
        subj:
          Men Who Have Sex With Men United States
          Pre-Exposure Prophylaxis
          Health Services Accessibility
          Human
          United States
          Decision Making
          Structural Equation Modeling
          Communication
          Stigma
          Autonomy
          Logistic Regression
          LGBTQ+ Persons
          HIV Infections Prevention and Control
          Bisexual Persons
          Adolescence
          Implementation Science
          Cisgender Persons
          Adolescent: 13-18 years
      ab: Access to daily oral pre-exposure prophylaxis (PrEP) is suboptimal among young cisgender men who have sex with men (YMSM) in the United States. Next-generation modalities that do not involve daily oral regimens may mitigate some of the barriers to PrEP use. We identified latent classes of YMSM based on health care decision-making patterns and examined associations between latent classes and access to health care and PrEP modality preferences (i.e., daily and event-driven oral, rectal douches, broadly neutralizing antibodies, subcutaneous implants, and an injectable). Between October 2020 and June 2021, we administered an online survey to 737 YMSM. Latent class analysis (LCA) identified groups of YMSM based on communication with providers, stigma and mistrust in health care, and autonomy in sexual health decisions. Logistic regression examined associations between class membership and health care access, and exploded logit regression examined associations between class membership and ranked PrEP modality preferences. LCA identified three classes: shared decision-making (high communication with providers and high autonomy); provider-led decision-making (high communication and low autonomy); and patient-driven decision-making (low communication and high autonomy). Shared decision-making was associated with higher access to health care in comparison with the other classes. Across all classes, YMSM preferred daily oral PrEP over all next-generation PrEP modalities. Preferences for daily oral PrEP over next-generation PrEP modalities were particularly marked among the patient-driven decision-making class. Shared decision-making is associated with access to health care and HIV prevention and higher acceptability of next-generation PrEP modalities, and should be considered as part of future interventions to promote use of daily oral and next-generation PrEP.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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