Plasma HDL pattern, cholesterol efflux and cholesterol loading capacity of serum in carriers of a novel missense variant (Gly176Trp) of endothelial lipase.

• Phenotypic description of family members with primary hyperalphalipoproteinemia. • Identification of a novel likely pathogenic variant of LIPG in three subjects. • Large HDL particles and reduced preβ-HDL content found in variant carriers. • Decreased ABCA1- and ABCG1-mediated cholesterol efflux c...

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Bibliographic Details

Published in:	Journal of Clinical Lipidology Vol. 16; no. 5; pp. 694 - 704
Main Authors:	Pisciotta, Livia, Ossoli, Alice, Ronca, Annalisa, Garuti, Anna, Fresa, Raffaele, Favari, Elda, Calabresi, Laura, Calandra, Sebastiano, Bertolini, Stefano
Format:	research Journal Article
Published:	Elsevier B.V. Sep2022
Online Access:	View this record in EBSCOhost