Full and simplified assessment of left ventricular diastolic function in covid‐19 patients admitted to ICU: Feasibility, incidence, and association with mortality.

Purpose: Left ventricular diastolic dysfunction (LVDD) is associated with poor outcomes in the intensive care unit (ICU). Nonetheless, precise reporting of LVDD in COVID‐19 patients is currently lacking and assessment could be challenging. Methods: We performed an echocardiography study in COVID‐19...

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Publicado en:Echocardiography Vol. 39; no. 11; pp. 1391 - 1401
Autores principales: La Via, Luigi, Dezio, Veronica, Santonocito, Cristina, Astuto, Marinella, Morelli, Andrea, Huang, Stephen, Vieillard‐Baron, Antoine, Sanfilippo, Filippo
Formato: diagnostic images research tables/charts Journal Article
Publicado: Wiley-Blackwell Nov2022
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Full and simplified assessment of left ventricular diastolic function in covid‐19 patients admitted to ICU: Feasibility, incidence, and association with mortality.
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        au:
          La Via, Luigi
          Dezio, Veronica
          Santonocito, Cristina
          Astuto, Marinella
          Morelli, Andrea
          Huang, Stephen
          Vieillard‐Baron, Antoine
          Sanfilippo, Filippo
        affil: Department of Anaesthesia and Intensive Care, "Policlinico‐San Marco" University Hospital, Catania, Italy
      sug:
        subj:
          Ventricular Dysfunction, Left Epidemiology
          Diastolic Pressure
          COVID-19
          Intensive Care Units
          Ventricular Dysfunction, Left Ultrasonography
          Hospital Mortality
          Human
          Survivors
          Outcomes (Health Care)
          Critically Ill Patients
          Severity of Illness
      ab: Purpose: Left ventricular diastolic dysfunction (LVDD) is associated with poor outcomes in the intensive care unit (ICU). Nonetheless, precise reporting of LVDD in COVID‐19 patients is currently lacking and assessment could be challenging. Methods: We performed an echocardiography study in COVID‐19 patients admitted to ICU with the aim to describe the feasibility of full or simplified LVDD assessment and its incidence. We also evaluated the association of LVDD or of single echocardiographic parameters with hospital mortality. Results: Between 06.10.2020 and 18.02.2021, full diastolic assessment was feasible in 74% (n = 26/35) of patients receiving a full echocardiogram study. LVDD incidence was 46% (n = 12/26), while the simplified assessment produced different results (incidence 81%, n = 21/26). Nine patients with normal function on full assessment had LVDD with simplified criteria (grade I = 2; grade II = 3; grade III = 4). Nine patients were hospital‐survivors (39%); the incidence of LVDD (full assessment) was not different between survivors (n = 2/9, 22%) and non‐survivors (n = 10/17, 59%; p =.11). The E/e' ratio lateral was lower in survivors (7.4 [3.6] vs. non‐survivors 10.5 [6.3], p =.03). We also found that s' wave was higher in survivors (average, p =.01). Conclusion: In a small single‐center study, assessment of LVDD according to the latest guidelines was feasible in three quarters of COVID‐19 patients. Non‐survivors showed a trend toward greater LVDD incidence; moreover, they had significantly worse s' values (all) and higher E/e' ratio (lateral).
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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