Escherichia coli sequence type 73 bloodstream infections in a centralized Canadian region and their association with companion animals: an ecological study.
Purpose: Extraintestinal pathogenic E. coli (ExPEC) are important pathogens causing community-acquired infections in humans, including bloodstream infections (BSIs), and may also colonize and infect animals. Our aim was to investigate associations between incidence rates (IRs) of BSIs caused by ExPE...
| Publicado en: | Infection Vol. 50; no. 6; pp. 1579 - 1586 |
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| Autores principales: | , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Springer Nature
Dec2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=160459271&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 160459271 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03008126 NXO jtl: Infection issn: 03008126 maglogo: N pubinfo: dt: Dec2022 vid: 50 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 160459271 157211481 160459271 160459271 10.1007/s15010-022-01856-1 160459271 ppf: 1579 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Escherichia coli sequence type 73 bloodstream infections in a centralized Canadian region and their association with companion animals: an ecological study. aug: au: Nobrega, Diego Peirano, Gisele Pitout, Johann D. D. affil: Department of Population Medicine, Ontario Veterinary College, University of Guelph, 50 Stone Road East, N1G 2W1, Guelph, ON, Canada sug: subj: Bacteremia Epidemiology Escherichia Coli Infections Epidemiology Pets Dogs Cats Sequence Analysis Human Canada Escherichia Coli Incidence Alberta Polymorphism, Single Nucleotide Polymerase Chain Reaction Descriptive Statistics Geographic Factors Catheter-Related Bloodstream Infections Risk Assessment ab: Purpose: Extraintestinal pathogenic E. coli (ExPEC) are important pathogens causing community-acquired infections in humans, including bloodstream infections (BSIs), and may also colonize and infect animals. Our aim was to investigate associations between incidence rates (IRs) of BSIs caused by ExPEC and number of dogs and cats in communities in Calgary. Methods: We used a well-characterized collection of blood isolates (n = 685) from Calgary, Alberta, Canada (2016). We used a combination of a seven-single-nucleotide-polymorphism quantitative PCR to type ExPEC into sequence types (STs). Calgary census data were used to estimate IRs per city community, as well as to investigate associations between number of companion animals per community, as obtained from licensing data, and IR of BSIs caused by each dominant ST. Results: From the 685 isolates available, ExPEC ST131 was most prevalent (21.3% of included isolates), followed by ST73 (13.7%), ST69 (8.2%), ST95 (6.7%), and ST1193 (5.3%), respectively. Incidence of BSIs caused by ExPECs among Calgary residents was 48.8 cases per 100,000 resident-years, whereas communities had on average of 1.7 companion animals per 10 residents. No association between the number of dogs and IR of BSIs caused by ExPECs was detected for any ST. Conversely, the incidence rate of BSIs caused by ST73 was 3.6 times higher (95%CI 1.3–9.99) for every increase of 1 cat per 10 habitants in communities. Conclusions: Number of cats per habitant was positively associated with the incidence of BSIs caused by ExPEC ST73. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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