An Efficient Optimization Approach for Glioma Tumor Segmentation in Brain MRI.

Glioma is an aggressive type of cancer that develops in the brain or spinal cord. Due to many differences in its shape and appearance, accurate segmentation of glioma for identifying all parts of the tumor and its surrounding cancerous tissues is a challenging task. In recent researches, the combina...

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Publicado en:Journal of Digital Imaging Vol. 35; no. 6; pp. 1634 - 1648
Autores principales: Barzegar, Zeynab, Jamzad, Mansour
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Dec2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2022
      vid: 35
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-022-00655-2
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        atl: An Efficient Optimization Approach for Glioma Tumor Segmentation in Brain MRI.
      aug:
        au:
          Barzegar, Zeynab
          Jamzad, Mansour
        affil: Sharif University of Technology, Tehran, Iran
      sug:
        subj:
          Brain Neoplasms Pathology
          Glioma Pathology
          Brain Neoplasms Diagnosis
          Glioma Diagnosis
          Brain Radiography
          Magnetic Resonance Imaging Methods
          Cervical Atlas
          Machine Learning
          Minimum Data Set
          Technology, Medical
          Neoplasm Grading
          Neoplasm Staging
          Human
          Models, Statistical
      ab: Glioma is an aggressive type of cancer that develops in the brain or spinal cord. Due to many differences in its shape and appearance, accurate segmentation of glioma for identifying all parts of the tumor and its surrounding cancerous tissues is a challenging task. In recent researches, the combination of multi-atlas segmentation and machine learning methods provides robust and accurate results by learning from annotated atlas datasets. To overcome the side effects of limited existing information on atlas-based segmentation, and the long training phase of learning methods, we proposed a semi-supervised unified framework for multi-label segmentation that formulates this problem in terms of a Markov Random Field energy optimization on a parametric graph. To evaluate the proposed framework, we apply it to publicly available BRATS datasets, including low- and high-grade glioma tumors. Experimental results indicate competitive performance compared to the state-of-the-art methods. Compared with the top ranked methods, the proposed framework obtains the best dice score for segmenting of "whole tumor" (WT), "tumor core" (TC) and "enhancing active tumor" (ET) regions. The achieved accuracy is 94 % characterized by the mean dice score. The motivation of using MRF graph is to map the segmentation problem to an optimization model in a graphical environment. Therefore, by defining perfect graph structure and optimum constraints and flows in the continuous max-flow model, the segmentation is performed precisely.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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