Application of Artificial Intelligence Computer-Assisted Diagnosis Originally Developed for Thyroid Nodules to Breast Lesions on Ultrasound.

As thyroid and breast cancer have several US findings in common, we applied an artificial intelligence computer-assisted diagnosis (AI-CAD) software originally developed for thyroid nodules to breast lesions on ultrasound (US) and evaluated its diagnostic performance. From January 2017 to December 2...

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Publicado en:Journal of Digital Imaging Vol. 35; no. 6; pp. 1699 - 1708
Autores principales: Lee, Si Eun, Lee, Eunjung, Kim, Eun-Kyung, Yoon, Jung Hyun, Park, Vivian Youngjean, Youk, Ji Hyun, Kwak, Jin Young
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: Springer Nature Dec2022
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: Application of Artificial Intelligence Computer-Assisted Diagnosis Originally Developed for Thyroid Nodules to Breast Lesions on Ultrasound.
      aug:
        au:
          Lee, Si Eun
          Lee, Eunjung
          Kim, Eun-Kyung
          Yoon, Jung Hyun
          Park, Vivian Youngjean
          Youk, Ji Hyun
          Kwak, Jin Young
        affil: Department of Radiology, Yongin Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea
      sug:
        subj:
          Thyroid Nodule Diagnosis
          Breast Neoplasms Diagnosis
          Artificial Intelligence
          Diagnosis, Computer Assisted
          Ultrasonography
          Human
          South Korea
          Female
          Adult
          Middle Age
          Aged
          Retrospective Design
          Biopsy, Needle
          Neural Networks (Computer)
          Software
          Image Processing, Computer Assisted
          ROC Curve
          Confidence Intervals
          Descriptive Statistics
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Female
      ab: As thyroid and breast cancer have several US findings in common, we applied an artificial intelligence computer-assisted diagnosis (AI-CAD) software originally developed for thyroid nodules to breast lesions on ultrasound (US) and evaluated its diagnostic performance. From January 2017 to December 2017, 1042 breast lesions (mean size 20.2 ± 11.8 mm) of 1001 patients (mean age 45.9 ± 12.9 years) who underwent US-guided core-needle biopsy were included. An AI-CAD software that was previously trained and validated with thyroid nodules using the convolutional neural network was applied to breast nodules. There were 665 benign breast lesions (63.0%) and 391 breast cancers (37.0%). The area under the receiver operating characteristic curve (AUROC) of AI-CAD to differentiate breast lesions was 0.678 (95% confidence interval: 0.649, 0.707). After fine-tuning AI-CAD with 1084 separate breast lesions, the diagnostic performance of AI-CAD markedly improved (AUC 0.841). This was significantly higher than that of radiologists when the cutoff category was BI-RADS 4a (AUC 0.621, P < 0.001), but lower when the cutoff category was BI-RADS 4b (AUC 0.908, P < 0.001). When applied to breast lesions, the diagnostic performance of an AI-CAD software that had been developed for differentiating malignant and benign thyroid nodules was not bad. However, an organ-specific approach guarantees better diagnostic performance despite the similar US features of thyroid and breast malignancies.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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