Myocardial Function Prediction After Coronary Artery Bypass Grafting Using MRI Radiomic Features and Machine Learning Algorithms.

The main aim of the present study was to predict myocardial function improvement in cardiac MR (LGE-CMR) images in patients after coronary artery bypass grafting (CABG) using radiomics and machine learning algorithms. Altogether, 43 patients who had visible scars on short-axis LGE-CMR images and wer...

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Publicado en:Journal of Digital Imaging Vol. 35; no. 6; pp. 1708 - 1719
Autores principales: Arian, Fatemeh, Amini, Mehdi, Mostafaei, Shayan, Rezaei Kalantari, Kiara, Haddadi Avval, Atlas, Shahbazi, Zahra, Kasani, Kianosh, Bitarafan Rajabi, Ahmad, Chatterjee, Saikat, Oveisi, Mehrdad, Shiri, Isaac, Zaidi, Habib
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Dec2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2022
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-022-00681-0
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        atl: Myocardial Function Prediction After Coronary Artery Bypass Grafting Using MRI Radiomic Features and Machine Learning Algorithms.
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          Arian, Fatemeh
          Amini, Mehdi
          Mostafaei, Shayan
          Rezaei Kalantari, Kiara
          Haddadi Avval, Atlas
          Shahbazi, Zahra
          Kasani, Kianosh
          Bitarafan Rajabi, Ahmad
          Chatterjee, Saikat
          Oveisi, Mehrdad
          Shiri, Isaac
          Zaidi, Habib
        affil: Department of Medical Physics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
      sug:
        subj:
          Coronary Artery Bypass
          Magnetic Resonance Imaging
          Machine Learning
          Algorithms
          Myocardium Physiology
          Prediction Models
          Radiomics
          Human
          Confidence Intervals
          Descriptive Statistics
          Multivariate Analysis
      ab: The main aim of the present study was to predict myocardial function improvement in cardiac MR (LGE-CMR) images in patients after coronary artery bypass grafting (CABG) using radiomics and machine learning algorithms. Altogether, 43 patients who had visible scars on short-axis LGE-CMR images and were candidates for CABG surgery were selected and enrolled in this study. MR imaging was performed preoperatively using a 1.5-T MRI scanner. All images were segmented by two expert radiologists (in consensus). Prior to extraction of radiomics features, all MR images were resampled to an isotropic voxel size of 1.8 × 1.8 × 1.8 mm3. Subsequently, intensities were quantized to 64 discretized gray levels and a total of 93 features were extracted. The applied algorithms included a smoothly clipped absolute deviation (SCAD)–penalized support vector machine (SVM) and the recursive partitioning (RP) algorithm as a robust classifier for binary classification in this high-dimensional and non-sparse data. All models were validated with repeated fivefold cross-validation and 10,000 bootstrapping resamples. Ten and seven features were selected with SCAD-penalized SVM and RP algorithm, respectively, for CABG responder/non-responder classification. Considering univariate analysis, the GLSZM gray-level non-uniformity-normalized feature achieved the best performance (AUC: 0.62, 95% CI: 0.53–0.76) with SCAD-penalized SVM. Regarding multivariable modeling, SCAD-penalized SVM obtained an AUC of 0.784 (95% CI: 0.64–0.92), whereas the RP algorithm achieved an AUC of 0.654 (95% CI: 0.50–0.82). In conclusion, different radiomics texture features alone or combined in multivariate analysis using machine learning algorithms provide prognostic information regarding myocardial function in patients after CABG.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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