Severity detection of COVID-19 infection with machine learning of clinical records and CT images.

Background: Coronavirus disease 2019 (COVID-19) is a deadly viral infection spreading rapidly around the world since its outbreak in 2019. In the worst case a patient's organ may fail leading to death. Therefore, early diagnosis is crucial to provide patients with adequate and effective treatment.Ob...

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Publicado en:Technology & Health Care Vol. 30; no. 6; pp. 1299 - 1315
Autores principales: Fubao Zhu, Zelin Zhu, Yijun Zhang, Hanlei Zhu, Zhengyuan Gao, Xiaoman Liu, Guanbin Zhou, Yan Xu, Fei Shan, Zhu, Fubao, Zhu, Zelin, Zhang, Yijun, Zhu, Hanlei, Gao, Zhengyuan, Liu, Xiaoman, Zhou, Guanbin, Xu, Yan, Shan, Fei
Formato: Journal Article
Publicado: Sage Publications Inc. 2022
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Sage Publications Inc.
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        10.3233/thc-220321
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        atl: Severity detection of COVID-19 infection with machine learning of clinical records and CT images.
      aug:
        au:
          Fubao Zhu
          Zelin Zhu
          Yijun Zhang
          Hanlei Zhu
          Zhengyuan Gao
          Xiaoman Liu
          Guanbin Zhou
          Yan Xu
          Fei Shan
          Zhu, Fubao
          Zhu, Zelin
          Zhang, Yijun
          Zhu, Hanlei
          Gao, Zhengyuan
          Liu, Xiaoman
          Zhou, Guanbin
          Xu, Yan
          Shan, Fei
        affil: School of Computer and Communication Engineering, Zhengzhou University of Light Industry, Zhengzhou, Henan, China
      sug:
      ab: Background: Coronavirus disease 2019 (COVID-19) is a deadly viral infection spreading rapidly around the world since its outbreak in 2019. In the worst case a patient's organ may fail leading to death. Therefore, early diagnosis is crucial to provide patients with adequate and effective treatment.Objective: This paper aims to build machine learning prediction models to automatically diagnose COVID-19 severity with clinical and computed tomography (CT) radiomics features.Method: P-V-Net was used to segment the lung parenchyma and then radiomics was used to extract CT radiomics features from the segmented lung parenchyma regions. Over-sampling, under-sampling, and a combination of over- and under-sampling methods were used to solve the data imbalance problem. RandomForest was used to screen out the optimal number of features. Eight different machine learning classification algorithms were used to analyze the data.Results: The experimental results showed that the COVID-19 mild-severe prediction model trained with clinical and CT radiomics features had the best prediction results. The accuracy of the GBDT classifier was 0.931, the ROUAUC 0.942, and the AUCPRC 0.694, which indicated it was better than other classifiers.Conclusion: This study can help clinicians identify patients at risk of severe COVID-19 deterioration early on and provide some treatment for these patients as soon as possible. It can also assist physicians in prognostic efficacy assessment and decision making.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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