Exploration of barriers and facilitators to the implementation of the DREPADO randomized controlled trial: A qualitative study.

DREPADO is a randomized controlled trial (RCT) assessing the impact of a pediatric-adult transition program, on the health status of adolescents with sickle cell disease. Using a biopsychosocial approach with three main facets (educational, psychological and social interactions), it constitutes a co...

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Published in:Journal of Pediatric Nursing Vol. 67; pp. 88 - 95
Main Authors: Bourron, Pierre, Cannas, Giovanna, Janoly-Dumenil, Audrey, Dussart, Claude, Gauthier-Vasserot, Alexandra, Hoegy, Delphine
Format: research Journal Article
Published: W B Saunders Nov2022
Online Access:View this record in EBSCOhost
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      dt: Nov2022
      vid: 67
      pid: 1351
      pub: W B Saunders
      place: Philadelphia, Pennsylvania
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        160583291
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        10.1016/j.pedn.2022.08.010
        160583291
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        atl: Exploration of barriers and facilitators to the implementation of the DREPADO randomized controlled trial: A qualitative study.
      aug:
        au:
          Bourron, Pierre
          Cannas, Giovanna
          Janoly-Dumenil, Audrey
          Dussart, Claude
          Gauthier-Vasserot, Alexandra
          Hoegy, Delphine
        affil: Institute of Pharmaceutical and Biological Sciences, Lyon 1 University, Lyon, France
      sug:
        subj:
          Anemia, Sickle Cell Therapy
          Transitional Care
          Transitional Programs
          Program Evaluation
          Randomized Controlled Trials
          Human
          Qualitative Studies
          Semi-Structured Interview
          Health Personnel
          Adolescence
          Adult
          Health Status
          Implementation Science
          Adolescent: 13-18 years
          Adult: 19-44 years
      ab: DREPADO is a randomized controlled trial (RCT) assessing the impact of a pediatric-adult transition program, on the health status of adolescents with sickle cell disease. Using a biopsychosocial approach with three main facets (educational, psychological and social interactions), it constitutes a complex transition program, which is quite difficult to implement. To facilitate the implementation of this complex program, the aim of this ancillary study is to explore barriers and facilitators at the early stages of this implementation. A qualitative study with semi-structured interviews was conducted, according to COREQ quality criteria, in patients with sickle cell disease who had already experienced the transition to adult care before DREPADO, and healthcare professionals working on the DREPADO RCT. Semi-structured interviews were conducted with patients (n = 12) and healthcare professionals (n = 12) from November 2019 to May 2020. The main barriers identified by patients were time and implication required by this transition program. Healthcare professionals involved in the coordinating center mentioned changes in their working habits and also elements about the RCT regulatory procedures. Main facilitators reported by both patients and healthcare professionals were the positive perception of the transition program design, and especially the home setting for therapeutic education sessions. This study led to the identification of main barriers and facilitators to the implementation of both the DREPADO intervention and RCT. These propositions could also be used to promote other complex public health interventions or/and other randomized controlled trials.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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