Massage of Bladder Meridian Relieved Anxiety Induced by Chronic Stress in Rats.

The aim of this paper was to explore the mechanism of bladder meridian massage (BMM) on anxiety in rats with chronic stress. Chronic stress induced rats to establish rat anxiety model. The sugar water preference (SPF), tail suspension time (TST), and forced swimming time (FST) of rats were measured....

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Publicado en:BioMed Research International pp. 1 - 7
Autores principales: Lu, Ping, Fang, Min, Yao, Lei, Zhang, Nan, Xu, Ke, He, Pei
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 12/8/2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 12/8/2022
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2022/5639716
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        atl: Massage of Bladder Meridian Relieved Anxiety Induced by Chronic Stress in Rats.
      aug:
        au:
          Lu, Ping
          Fang, Min
          Yao, Lei
          Zhang, Nan
          Xu, Ke
          He, Pei
        affil: College of Acupuncture and Massage, Shanghai University of Chinese Medicine, China
      sug:
        subj:
          Massage
          Bladder
          Meridians
          Anxiety Therapy
          Stress, Psychological
          Chronic Disease
          Models, Biological
          Animal Studies
          Rats
          Superoxide Dismutase Analysis
          Malondialdehyde Analysis
          Cytokines Analysis
          Inflammation
          Serum
          Hippocampus
          Enzyme-Linked Immunosorbent Assay
          Neurotransmitters Analysis
          Blotting, Western
          Autophagy-Related Proteins Analysis
          Behavior, Animal Evaluation
          Depression Therapy
          Immunohistochemistry
          Staining and Labeling
          Analysis of Variance
          Post Hoc Analysis
          Data Analysis Software
          Interleukins Analysis
      ab: The aim of this paper was to explore the mechanism of bladder meridian massage (BMM) on anxiety in rats with chronic stress. Chronic stress induced rats to establish rat anxiety model. The sugar water preference (SPF), tail suspension time (TST), and forced swimming time (FST) of rats were measured. The levels of superoxide dismutase (SOD), malondialdehyde (MDA), and inflammatory cytokines in serum and hippocampus of rats were detected. Brain neurotransmitters (dopamine (DA), 5- hydroxytryptamine (5-HT), and norepinephrine (NE)) were detected by enzyme-linked immunosorbent assay (ELISA) kits. Immunohistochemistry and western blotting were used to detect autophagy protein expression in hippocampus of rats. BMM significantly increased SPF, decreased TST and FST, increased SOD level in serum and hippocampus, and decreased MDA level and cytokine level. BMM reversed the changes of neurotransmitters. At the same time, BMM significantly decreased autophagy protein expression in hippocampus of rats. The above results show that BMM significantly relieve anxiety induced by chronic stress in rats.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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