Comparison of Neurocognitive Functioning and Fine Motor Skills in Pediatric Cancer Survivors and Healthy Children.
Simple Summary: Various impairments in neurocognitive and fine motor skills represent a common side effect of both pediatric tumors and their therapy in children. Here we compare the neurocognitive and fine motor skills deficits manifested in the group with pediatric tumors against the background of...
| Publicado en: | Cancers Vol. 14; no. 23; pp. 5982 - 5998 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
MDPI
Dec2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=160714551&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 160714551 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 20726694 B74B jtl: Cancers issn: 20726694 maglogo: N pubinfo: dt: Dec2022 vid: 14 iid: 23 pid: 97109 pub: MDPI artinfo: ui: 160714551 160714551 160714551 10.3390/cancers14235982 160714551 ppf: 5982 ppct: 16 formats: tig: atl: Comparison of Neurocognitive Functioning and Fine Motor Skills in Pediatric Cancer Survivors and Healthy Children. aug: au: Chipeeva, Nadezda Deviaterikova, Alena Glebova, Elena Romanova, Elizaveta Karelin, Alexander Kasatkin, Vladimir affil: Research Institute for Brain Development and Peak Performance, Peoples Friendship University of Russia, 117198 Moscow, Russia sug: subj: Cognition Motor Skills Cancer Survivors In Infancy and Childhood Human Treatment Outcomes Motor Skills Disorders Complications Cognition Disorders Complications Adaptation, Psychological Memory Spatial Perception Motor Skills Evaluation Speech Evaluation Hematologic Neoplasms Lymphatic Diseases Female Male Child Child: 6-12 years Female Male ab: Simple Summary: Various impairments in neurocognitive and fine motor skills represent a common side effect of both pediatric tumors and their therapy in children. Here we compare the neurocognitive and fine motor skills deficits manifested in the group with pediatric tumors against the background of the healthy control group. Worse impairments of neurocognitive and fine motor skill were revealed in pediatric brain tumor survivors as compared with hematopoietic and lymphoid tissue tumor survivors. Significant differences between the cognitive functions of females and males were detected only in the pediatric brain tumor survivors group. Background: The late treatment outcomes of pediatric brain tumors and of hematopoietic and lymphoid tissue tumors are an important focus of both rehabilitation and research. Neurocognitive and motor disorders induce further learning problems impeding social-emotional adaptation throughout a whole lifespan. Core deficits in short-term and working memory, visuospatial constructional ability, verbal fluency, and fine motor skills underlie distorted intellectual and academic achievement. This study aimed to assess the individual differences in cognitive ability and fine motor skills of pediatric tumor survivors and the age-matched healthy controls. Methods: A total of 504 tumor survivors after treatment and 646 age-matched healthy controls underwent neurocognitive and fine motor assessments. Findings: The group of tumor survivors scored significantly worse in both neurocognitive and fine motor skill in compared with the healthy control group. The pediatric brain tumor survivors (PBT group) performed worse in cognitive (p < 0.001 for verbal fluency and p < 0.001 for visuospatial constructional ability) and motor tests (p < 0.001) compared to the healthy controls. Hematopoietic and Lymphoid Tissues tumors survivors (THL group) performed worse in verbal fluency (p < 0.01) and visuospatial constructional test (p < 0.001) compared to the control group. Furthermore, the PBT group had worse results in visuospatial constructional ability (p < 0.05) and fine motor (p < 0.001) ability than the THL group. Significant differences between females and males were found in fine motor test performance in the PBT group (p < 0.05), as well as in verbal fluency (p < 0.01) and visuospatial constructional ability (p < 0.01) in the control group. Neurocognitive and fine motor skill characteristics in the THL group did not correlate with age. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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