Integrating Pharmacogenomics Data-Driven Computational Drug Prediction with Single-Cell RNAseq to Demonstrate the Efficacy of a NAMPT Inhibitor against Aggressive, Taxane-Resistant, and Stem-like Cells in Lethal Prostate Cancer.

Simple Summary: Prostate cancer (PCa) is the second most common cancer and the second leading cause of cancer deaths in US men. Resistance to standard medical castration and secondary taxane-based chemotherapy, the presence of cancer stem-like cells representing epithelial to mesenchymal transdiffer...

Full description

Bibliographic Details

Published in:	Cancers Vol. 14; no. 23; pp. 6009 - 6048
Main Authors:	Mazumder, Suman, Mitra Ghosh, Taraswi, Mukherjee, Ujjal K., Chakravarti, Sayak, Amiri, Farshad, Waliagha, Razan S., Hemmati, Farnaz, Mistriotis, Panagiotis, Ahmed, Salsabil, Elhussin, Isra, Salam, Ahmad-Bin, Dean-Colomb, Windy, Yates, Clayton, Arnold, Robert D., Mitra, Amit K.
Format:	equations & formulas pictorial research tables/charts Journal Article
Published:	MDPI Dec2022
Online Access:	View this record in EBSCOhost