A Quantitative and Qualitative Assessment of Frozen Section Diagnosis Accuracy and Deferral Rate Across Organ Systems.
Objectives: Monitoring of frozen section diagnostic performance provides an important quality improvement measure.Methods: Surgical specimens involving a frozen section diagnosis over a 3-year period were retrospectively reviewed. Glass slides were reviewed on cases with discordance. Discordance and...
| Publicado en: | American Journal of Clinical Pathology Vol. 158; no. 6; pp. 692 - 702 |
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| Autores principales: | , , , , , , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Oxford University Press / USA
Dec2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=160777706&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 160777706 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00029173 2RW jtl: American Journal of Clinical Pathology issn: 00029173 maglogo: N pubinfo: dt: Dec2022 vid: 158 iid: 6 pid: 10398 pub: Oxford University Press / USA artinfo: ui: 160777706 160777706 NLM36197800 10.1093/ajcp/aqac115 NLM36197800 160777706 ppf: 692 ppct: 10 formats: tig: atl: A Quantitative and Qualitative Assessment of Frozen Section Diagnosis Accuracy and Deferral Rate Across Organ Systems. aug: au: Mohamed, Anas Hassan, Muhammad Masood Zhong, Wen Kousar, Aisha Takeda, Kotaro Donthi, Deepak Rizvi, Areeba Majeed, Marwan Younes, Ahmed I Ali, Ahlam Sutton, Ann Murray, Gina Thayyil, Abdullah Fallon, John Geisinger, Kim affil: Department of Pathology and Laboratory Medicine, East Carolina University/Vidant Medical Center , Greenville, NC , USA sug: subj: Frozen Sections Methods Pathology Methods Female Diagnostic Errors Prevention and Control Retrospective Design Intraoperative Period Ferrans and Powers Quality of Life Index Female ab: Objectives: Monitoring of frozen section diagnostic performance provides an important quality improvement measure.Methods: Surgical specimens involving a frozen section diagnosis over a 3-year period were retrospectively reviewed. Glass slides were reviewed on cases with discordance. Discordance and deferral rates were calculated.Results: Of 3,675 frozen section diagnoses included, 96 (2.7%) were discordant with the final diagnosis. Additionally, 114 frozen section diagnoses (3.1%) were deferred. The organ-specific discordance rates were lowest in breast and genitourinary specimens and highest for pancreas, lymph node, and gynecologic specimens. Deferral rates were highest in musculoskeletal, breast, and hepatobiliary cases and lowest in thyroid, parathyroid, and neuropathology cases. Discordance was explained by block-sampling error (45%), specimen-sampling error (27%), or interpretation error (27%). Discordant frozen section diagnoses from gynecologic specimens were responsible for 81% of specimen-sampling errors; frozen section diagnoses of lymph nodes, head and neck, and pancreas were responsible for 54% of interpretation errors; 51% of block-sampling errors involved lymph node evaluation for metastatic carcinoma.Conclusions: Careful gross evaluation and microscopic examination of multiple levels should minimize specimen-sampling error and block-sampling error, respectively. Periodic review of accuracy and deferral rates may help reduce errors and improve the overall performance of this essential procedure. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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