| Sumario: | Across the trajectory of children with acute lymphoblastic leukemia undergoing chemotherapy, these childhood health conditions are major life-threatening illnesses that affect life changes and impact quality of life of the entire family. This quasi-experimental study examined the effectiveness of a Family-Based Intervention Program for family members of preschool children with acute lymphoblastic leukemia undergoing chemotherapy to help improve their quality of life. Participants were the dyad of 54 children, 3-5-year-olds diagnosed with acute lymphoblastic leukemia, and their family members from two hospitals. The intervention group (n = 27) received a 6-week family-based intervention program in addition to usual care, whereas the control group (n = 27) received only usual care. Data were collected using the family quality of life questionnaires and were analyzed using an independent t-test. The results indicated that two weeks after completing the program, family quality of life in the experimental group was significantly higher than in the control group, indicating that this program is useful for improving the family's quality of life. Thus, the program can be useful for nurses, including advanced practice nurses as clinical leaders to provide continuous care for this group of children and family members. However, further study using randomized controlled trials is needed before the program is implemented into clinical practice.
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