Variability in Cardiopulmonary Exercise Testing Biologic Controls.
BACKGROUND: Cardiopulmonary exercise testing is an increasingly common test and is considered the accepted standard for assessing exercise capacity. Quantifying variability is important to assess the instrument for quality control purposes. Though guidelines recommend biologic control testing, there...
| Publicado en: | Respiratory Care Vol. 68; no. 1; pp. 38 - 44 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Mary Ann Liebert, Inc.
Jan2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=160923586&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 160923586 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00201324 4GG jtl: Respiratory Care issn: 00201324 maglogo: N pubinfo: dt: Jan2023 vid: 68 iid: 1 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 160923586 160923586 160923586 10.4187/respcare.10022 160923586 ppf: 38 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Variability in Cardiopulmonary Exercise Testing Biologic Controls. aug: au: DeCato, Thomas W. Haverkamp, Hans C. Gooding, Thomas Collingridge, Dave S. Hegewald, Matthew J. affil: Division of Respiratory and Critical Care Physiology and Medicine and The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California sug: subj: Exercise Test, Cardiopulmonary Biological Factors Pulmonary Gas Exchange Human Prospective Studies Male Female Ergometry Descriptive Statistics Significance Test Adult Middle Age Anaerobic Threshold Oxygen Consumption Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: BACKGROUND: Cardiopulmonary exercise testing is an increasingly common test and is considered the accepted standard for assessing exercise capacity. Quantifying variability is important to assess the instrument for quality control purposes. Though guidelines recommend biologic control testing, there are minimal data on how to do it. We sought to describe variability for oxygen consumption (...), carbon dioxide production (...), and minute ventilation (...) at various work rates under steady-state conditions in multiple subjects over a 1-y period to provide a practical approach to assess and perform biologic control testing. METHODS: We performed a single-center, prospective study with 4 healthy subjects, 2 men and 2 women. Subjects performed constant work rate exercise tests for 6 min each at 25-100 W intervals on a computer-controlled cycle ergometer. Data were averaged over the last 120 s at each work rate to reflect stepwise steady-state conditions. Descriptive statistics, including the mean, median, range, SD, and coefficient of variation (CoV) are reported for each individual across the 4 work rates and all repetitions. As these data were normative, z-scores were utilized, and a value greater than ± 1.96 z-scores was used to define significant test variability. RESULTS: Subjects performed 16-39 biocontrol studies over 1-y. The mean CoV for all subjects in ... was 6.59%, ... was 6.41%, and ... was 6.32%. The ± 1.96 z-scores corresponded to a 9.4-18.1% change in ... a 9.6-18.1% change in ..., and a 9-21.5% change in ... across the 4 workloads. CONCLUSIONS: We report long-term variability for steady-state measurement of ..., ..., and ... obtained during biocontrol testing. Utilizing ± 1.96 z-scores allows one to determine if a result exceeds expected variability, which may warrant investigation of the instrument. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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