Epidemiology of Weaning From Invasive Mechanical Ventilation in Subjects With COVID-19.
BACKGROUND: Patients requiring mechanical ventilation due to COVID-19 have different characteristics of evolution and outcome compared to the general ICU population. Although early weaning from mechanical ventilation is associated with improved outcomes, inadequate identification of patients unable...
| Publicado en: | Respiratory Care Vol. 68; no. 1; pp. 101 - 110 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Mary Ann Liebert, Inc.
Jan2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=160923594&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 160923594 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00201324 4GG jtl: Respiratory Care issn: 00201324 maglogo: N pubinfo: dt: Jan2023 vid: 68 iid: 1 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 160923594 160923594 160923594 10.4187/respcare.09925 160923594 ppf: 101 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Epidemiology of Weaning From Invasive Mechanical Ventilation in Subjects With COVID-19. aug: au: Dorado, Javier H. Navarro, Emiliano Plotnikow, Gustavo A. Gogniat, Emiliano Accoce, Matías affil: Capítulo de Kinesiología Intensivista, Sociedad Argentina de Terapia Intensiva, CABA, Argentina sug: subj: Treatment Weaning Respiration, Artificial Methods COVID-19 Epidemiology Invasive Procedures Extubation, Traumatic Risk Factors Treatment Outcomes Respiratory Failure Multicenter Studies Prospective Studies Intensive Care Units Airway Management Methods Respiration, Artificial Classification Length of Stay Respiratory Distress Syndrome, Newborn Human Male Female Middle Age Aged Data Analysis Software Descriptive Statistics Kruskal-Wallis Test Confidence Intervals Middle Aged: 45-64 years Aged: 65+ years Male Female ab: BACKGROUND: Patients requiring mechanical ventilation due to COVID-19 have different characteristics of evolution and outcome compared to the general ICU population. Although early weaning from mechanical ventilation is associated with improved outcomes, inadequate identification of patients unable to be weaned may lead to extubation failure and increased days on mechanical ventilation. Outcomes related to mechanical ventilation weaning in this population are scare and inconclusive. Therefore, the objective of this study was to describe the characteristics of mechanical ventilation weaning in subjects with acute respiratory failure induced by COVID-19. METHODS: This was a multi-center, prospective cohort study. We included adult subjects requiring at least 12 h of mechanical ventilation due to COVID-19 infection admitted to any participating ICUs. Characteristics of the mechanical ventilation weaning and extubation process, as well as clinical results, were the primary outcome variables. Weaning types were defined according to previously described and internationally recognized categories. RESULTS: Three hundred twenty-six subjects from 8 ICUs were included. A spontaneous breathing trial (SBT) was not performed in 52.1% of subjects. One hundred twenty-eight subjects were extubated, and 29.7% required re-intubation. All the subjects included could be classified by Weaning according to a New Definition (WIND) classification (group 0 = 52.1%, group 1 = 28.5%, group 2 = 8.0%, and group 3 = 11.3%) with statistically significant differences in duration of mechanical ventilation (P < .001) and ICU length of stay (P < .001) between groups. CONCLUSIONS: The mechanical ventilation weaning process in subjects with COVID-19 was negatively affected by the disease, with many subjects never completing an SBT. Even though temporal variables were modified, the clinical outcomes in each weaning group were similar to those previously reported. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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