Pharmacokinetics and soft-tissue distribution of tebipenem pivoxil hydrobromide using microdialysis: a study in healthy subjects and patients with diabetic foot infections.

Objective: Tebipenem pivoxil hydrobromide is a novel oral carbapenem prodrug of tebipenem, the active moiety. We assessed tebipenem steady-state pharmacokinetics in the skin and soft tissue in healthy subjects and infected patients with diabetes using in vivo microdialysis.Methods: Six healthy subje...

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Bibliographic Details

Published in:	Journal of Antimicrobial Chemotherapy (JAC) Vol. 78; no. 1; pp. 296 - 302
Main Authors:	Abouelhassan, Yasmeen, Fratoni, Andrew J, Shepard, Ashley K, Nicolau, David P, Asempa, Tomefa E
Format:	Journal Article
Published:	Oxford University Press / USA Jan2023
Online Access:	View this record in EBSCOhost