Stratification of Length of Stay Prediction following Surgical Cytoreduction in Advanced High-Grade Serous Ovarian Cancer Patients Using Artificial Intelligence; the Leeds L-AI-OS Score.

(1) Background: Length of stay (LOS) has been suggested as a marker of the effectiveness of short-term care. Artificial Intelligence (AI) technologies could help monitor hospital stays. We developed an AI-based novel predictive LOS score for advanced-stage high-grade serous ovarian cancer (HGSOC) pa...

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Publicado en:Current Oncology Vol. 29; no. 12; pp. 9088 - 9105
Autores principales: Laios, Alexandros, De Freitas, Daniel Lucas Dantas, Saalmink, Gwendolyn, Tan, Yong Sheng, Johnson, Racheal, Zubayraeva, Albina, Munot, Sarika, Hutson, Richard, Thangavelu, Amudha, Broadhead, Tim, Nugent, David, Kalampokis, Evangelos, de Lima, Kassio Michell Gomes, Theophilou, Georgios, De Jong, Diederick
Formato: Journal Article
Publicado: MDPI Dec2022
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Stratification of Length of Stay Prediction following Surgical Cytoreduction in Advanced High-Grade Serous Ovarian Cancer Patients Using Artificial Intelligence; the Leeds L-AI-OS Score.
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        au:
          Laios, Alexandros
          De Freitas, Daniel Lucas Dantas
          Saalmink, Gwendolyn
          Tan, Yong Sheng
          Johnson, Racheal
          Zubayraeva, Albina
          Munot, Sarika
          Hutson, Richard
          Thangavelu, Amudha
          Broadhead, Tim
          Nugent, David
          Kalampokis, Evangelos
          de Lima, Kassio Michell Gomes
          Theophilou, Georgios
          De Jong, Diederick
        affil: ESGO Centre of Excellence for Ovarian Cancer Surgery, Department of Gynaecological Oncology, St James's University Hospital, Leeds Teaching Hospitals, Leeds LS9 7TF, UK
      sug:
      ab: (1) Background: Length of stay (LOS) has been suggested as a marker of the effectiveness of short-term care. Artificial Intelligence (AI) technologies could help monitor hospital stays. We developed an AI-based novel predictive LOS score for advanced-stage high-grade serous ovarian cancer (HGSOC) patients following cytoreductive surgery and refined factors significantly affecting LOS. (2) Methods: Machine learning and deep learning methods using artificial neural networks (ANN) were used together with conventional logistic regression to predict continuous and binary LOS outcomes for HGSOC patients. The models were evaluated in a post-hoc internal validation set and a Graphical User Interface (GUI) was developed to demonstrate the clinical feasibility of sophisticated LOS predictions. (3) Results: For binary LOS predictions at differential time points, the accuracy ranged between 70–98%. Feature selection identified surgical complexity, pre-surgery albumin, blood loss, operative time, bowel resection with stoma formation, and severe postoperative complications (CD3–5) as independent LOS predictors. For the GUI numerical LOS score, the ANN model was a good estimator for the standard deviation of the LOS distribution by ± two days. (4) Conclusions: We demonstrated the development and application of both quantitative and qualitative AI models to predict LOS in advanced-stage EOC patients following their cytoreduction. Accurate identification of potentially modifiable factors delaying hospital discharge can further inform services performing root cause analysis of LOS.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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