Biomarker Discordances and Alterations Observed in Breast Cancer Treated with Neoadjuvant Chemotherapy: Causes, Frequencies, and Clinical Significances.

Purpose: Biomarker discordances and alterations can be encountered between tru-cut biopsy and residual tumor in breast cancer treated with neoadjuvant chemotherapy (NACTx). We aimed to investigate the effect of NACTx on major biomarker expression (ER, PR, HER2, Ki-67) and tumor grade, the frequency...

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Bibliographic Details
Published in:Current Oncology Vol. 29; no. 12; pp. 9695 - 9711
Main Authors: Yilmaz, Cengiz, Cavdar, Demet Kocatepe
Format: Journal Article
Published: MDPI Dec2022
Online Access:View this record in EBSCOhost