Hydrogen Sulfide Protects Against Ischemic Heart Failure by Inhibiting RIP1/RIP3/MLKL-Mediated Necroptosis.

The aim of the present study was to explore whether hydrogen sulfide (H2S) protects against ischemic heart failure (HF) by inhibiting the necroptosis pathway. Mice were randomized into Sham, myocardial infarction (MI), MI + propargylglycine (PAG) and MI + sodium hydrosulfide (NaHS) group, respective...

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Bibliographic Details
Published in:Physiological Research Vol. 71; no. 6; pp. 771 - 782
Main Authors: Fenfen MA, Yahong ZHU, Lingling CHANG, Jingru GONG, Ying LUO, Jing DAI, Huiping LU
Format: Journal Article
Published: Institute of Physiology, Academy of Sciences of the Czech Republic Dec2022
Online Access:View this record in EBSCOhost