A comprehensive analysis and literature review of vertebral artery variation in craniovertebral junction using three-dimensional computed tomography angiography.

Purpose: To describe vertebral artery (VA) variation in patients with or without osseous anomalies at congenital craniovertebral junction (CVJ). Methods: In the present study, we retrospectively analyzed 258 patients with VA variation who underwent three-dimensional computed tomography angiography (...

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Published in:Neuroradiology Vol. 65; no. 1; pp. 215 - 224
Main Authors: Yang, Hao-Zhi, Liu, Guo-Qiang, Xia, Hong, Ma, Xiang-Yang, Wang, Jian-Hua
Format: pictorial research tables/charts Journal Article
Published: Springer Nature Jan2023
Online Access:View this record in EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: A comprehensive analysis and literature review of vertebral artery variation in craniovertebral junction using three-dimensional computed tomography angiography.
      aug:
        au:
          Yang, Hao-Zhi
          Liu, Guo-Qiang
          Xia, Hong
          Ma, Xiang-Yang
          Wang, Jian-Hua
        affil: Department of Orthopedics, General Hospital of Southern Theatre Command of PLA, 111 Liuhua Road, 510010, Guangzhou, People's Republic of China
      sug:
        subj:
          Vertebral Artery Physiology
          Craniovertebral Junction Abnormalities
          Imaging, Three-Dimensional
          Computed Tomography Angiography
          Retrospective Design
          Human
          Male
          Female
          Young Adult
          Adult
          Middle Age
          Aged
          Magnetic Resonance Imaging
          Cervical Atlas
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Purpose: To describe vertebral artery (VA) variation in patients with or without osseous anomalies at congenital craniovertebral junction (CVJ). Methods: In the present study, we retrospectively analyzed 258 patients with VA variation who underwent three-dimensional computed tomography angiography (3D CTA) in our hospital from March 2017 to October 2019. Results: Among 258 patients, 180 were accompanied by skeleton structural malformation, including 105 cases of occipital ossification of the atlas, 8 cases of the bipartite atlas, 7 cases of hypoplasia of the posterior arch of the atlas, 45 cases of C2/3 congenital fusion, 2 cases of C2/3/4 congenital fusion, and 13 cases of congenital os odontoid. VA variation was divided into type A (VA variation in the CVJ area without osseous anomalies) and type B (VA variation in the CVJ area with osseous anomalies). There are totally 10 subtypes, including type A1 (atlas occipitalization with VA entrance approach close to middle line, 20.2%); type A2 (atlas occipitalization with VA entrance approach far from middle line, 30.2%); type A3 (first intersegmental VA in C1–C2, 1.9%); type A4 (fenestration of the VA, 2.3%); type A5 (VA bulging type, 6.6%); type A6 (VA exposures with the absence of the posterior atlas arch, 2.3%); type A7 (C2 inner wall type, 0.4%); type A8 (single vertebral artery, 2.3%); type B1 (posterior ponticuli, 2.7%); and type B2 (high-riding VA, 31.4%). Conclusion: This study is expected to take the lead in the most comprehensive classification of VA variation.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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