Psychosocial Occupational Exposures and Mental Illness: A Systematic Review With Meta-Analyses.

Background: The purpose of this study is to investigate the exposure-risk relationship between psychosocial occupational stress and mental illness. Methods: We conducted a systematic review with meta-analyses as an update of a systematic review published in 2014. The study protocol was registered in...

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Published in:Deutsches Ärzteblatt International Vol. 119; no. 42; pp. 709 - 827
Main Authors: Seidler, Andreas, Schubert, Melanie, Freiberg, Alice, Drössler, Stephanie, Hussenoeder, Felix S., Conrad, Ines, Riedel-Heller, Steffi, Starke, Karla Romero
Format: Journal Article
Published: Deutscher Aerzte-Verlag GmbH 10/21/2022
Online Access:View this record in EBSCOhost
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      dt: 10/21/2022
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      pub: Deutscher Aerzte-Verlag GmbH
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        10.3238/arztebl.m2022.0295
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        atl: Psychosocial Occupational Exposures and Mental Illness: A Systematic Review With Meta-Analyses.
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        au:
          Seidler, Andreas
          Schubert, Melanie
          Freiberg, Alice
          Drössler, Stephanie
          Hussenoeder, Felix S.
          Conrad, Ines
          Riedel-Heller, Steffi
          Starke, Karla Romero
        affil: Institute and Policlinic of Occupational and Social Medicine (IPAS), Faculty of Medicine, TU Dresden, Dresden, Germany
      sug:
      ab: Background: The purpose of this study is to investigate the exposure-risk relationship between psychosocial occupational stress and mental illness. Methods: We conducted a systematic review with meta-analyses as an update of a systematic review published in 2014. The study protocol was registered in PROSPERO (CRD42020170032). Literature searches were carried out in the MEDLINE, PsycINFO, and Embase databases. All procedural steps were performed independently by two reviewers; discordances were solved by consensus. All of the included full texts were subject to a methodological appraisal. Certainty of evidence was determined with the GRADE procedure. Results: The pooled risk of depression was found to be approximately doubled in workers exposed to high job strain, which is defined as high work demands combined with low job control (effect estimate [EE] = 1.99, 95% CI [1.68; 2.35], heterogeneity [I2] = 24.7%, n = 8). In particular, high work demands are associated with incident depression (ES = 13.8 [1.19; 1.61], I2 = 69.0%, n = 9) and with incident anxiety disorder (ES = 1.79 [1.44; 2.23], I2 = 48.1%, n = 5). There were only a small number of methodologically adequate studies available on burnout, somatoform disorders, suicidal ideation, and suicide. Thus, no pooled risk estimates were calculated, although some individual studies showed a considerably increased risk. Conclusion: Psychosocial occupational stress is clearly associated with depression and anxiety disorders.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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