Phosphaturic mesenchymal tumor in right thigh: 2 cases report and literature review.

BACKGROUND: Phosphaturic mesenchymal tumor (PMT) is a very rare tumor of bone and soft tissue that has no specific clinical manifestations. Here we present 2 cases of PMT in the right thigh, including comparatively adequate immunohistochemistry. CASE PRESENTATION: We described 2 cases of PMT in the...

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Publicado en:Clinical Pathology Vol. 15; pp. 1 - 8
Autores principales: Ruifeng Wang, Jiayu Zhou, Yupei Yu, Junqi Deng, Ze Wu, Chunlin Ou, Yanhao Wu, Keda Yang, Junpu Wang
Formato: case study diagnostic images pictorial tables/charts Journal Article
Publicado: Sage Publications Inc. Jan-Dec2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan-Dec2022
      vid: 15
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        atl: Phosphaturic mesenchymal tumor in right thigh: 2 cases report and literature review.
      aug:
        au:
          Ruifeng Wang
          Jiayu Zhou
          Yupei Yu
          Junqi Deng
          Ze Wu
          Chunlin Ou
          Yanhao Wu
          Keda Yang
          Junpu Wang
        affil: Department of Pathology, Xiang-ya Hospital, Central South University, Changsha City, Hunan Province, China
      sug:
        subj:
          Thigh Pathology
          Bone Neoplasms
          Soft Tissue Neoplasms
          Osteomalacia
          Immunohistochemistry
          Hypophosphatemia
          Positron Emission Tomography Computed Tomography
          Microscopy
          Aged
          Male
          Adult
          Aged: 65+ years
          Adult: 19-44 years
          Male
      ab: BACKGROUND: Phosphaturic mesenchymal tumor (PMT) is a very rare tumor of bone and soft tissue that has no specific clinical manifestations. Here we present 2 cases of PMT in the right thigh, including comparatively adequate immunohistochemistry. CASE PRESENTATION: We described 2 cases of PMT in the right thigh with manifestations of hypophosphatemia. PET-CT examination showed that both patients had lesions with increased expression of somatostatin receptors in the right thigh. Bland cells and dirty calcified stroma were exhibited under the microscope. And immunohistochemical detection of FGF-23 was positive. CONCLUSIONS: PMT is a very uncommon tumor for which diagnosis and treatment are often delayed. Considering the importance of surgery for the treatment of this disease, a full understanding of its clinicopathological features will facilitate the diagnosis of this disease.
      pubtype: Academic Journal
      doctype:
        case study
        diagnostic images
        pictorial
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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