Surgical site wound infection, and other postoperative problems after coronary artery bypass grafting in subjects with chronic obstructive pulmonary disease: A meta‐analysis.

We performed a meta‐analysis to evaluate the effect of chronic obstructive pulmonary disease on surgical site wound infection, and other postoperative problems after coronary artery bypass grafting. A systematic literature search up to April 2022 was performed and 37 444 subjects with coronary arter...

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Published in:International Wound Journal Vol. 20; no. 2; pp. 302 - 313
Main Authors: Gao, Jinglin, Wang, Huijuan, Liu, Xiuhua, Song, Xinghui, Zhong, Xiaoning
Format: meta analysis research systematic review tables/charts Journal Article
Published: Wiley-Blackwell Feb2023
Online Access:View this record in EBSCOhost
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      dt: Feb2023
      vid: 20
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/iwj.13877
        161586996
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      tig:
        atl: Surgical site wound infection, and other postoperative problems after coronary artery bypass grafting in subjects with chronic obstructive pulmonary disease: A meta‐analysis.
      aug:
        au:
          Gao, Jinglin
          Wang, Huijuan
          Liu, Xiuhua
          Song, Xinghui
          Zhong, Xiaoning
        affil: Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China
      sug:
        subj:
          Pulmonary Disease, Chronic Obstructive Complications
          Coronary Artery Bypass Adverse Effects
          Postoperative Complications Risk Factors
          Surgical Wound Infection Risk Factors
          Risk Assessment
          Human
          Meta Analysis
          Descriptive Statistics
          Data Analysis Software
          Confidence Intervals
          Odds Ratio
          PubMed
          Embase
          Cochrane Library
      ab: We performed a meta‐analysis to evaluate the effect of chronic obstructive pulmonary disease on surgical site wound infection, and other postoperative problems after coronary artery bypass grafting. A systematic literature search up to April 2022 was performed and 37 444 subjects with coronary artery bypass grafting at the baseline of the studies; 4320 of them were with the chronic obstructive pulmonary disease, and 33 124 were without chronic obstructive pulmonary disease. Odds ratio (OR), and mean difference (MD) with 95% confidence intervals (CIs) were calculated to assess the effect of chronic obstructive pulmonary disease on surgical site wound infection, and other postoperative problems after coronary artery bypass grafting using the dichotomous, and contentious methods with a random or fixed‐effect model. The chronic obstructive pulmonary disease subjects had a significantly higher surgical site wound infection (OR, 1.27; 95% CI, 1.01‐1.60, P = 0.04), respiratory failure (OR, 1.84; 95% CI, 1.55‐2.18, P < 0.001), mortality (OR, 1.61; 95% CI, 1.37‐1.89, P < 0.001), pneumonia (OR, 2.30; 95% CI, 1.97‐2.68, P < 0.001), pleural effusion (OR, 1.78; 95% CI, 1.12‐2.83, P = 0.02), stroke (OR, 1.99; 95% CI, 1.17‐3.36, P = 0.01), and length of intensive care unit stay (MD, 0.73; 95% CI, 0.19‐1.26, P = 0.008) after coronary artery bypass grafting compared with subjects without chronic obstructive pulmonary disease. However, chronic obstructive pulmonary disease subjects did not show any significant difference in length of hospital stay (MD, 0.83; 95% CI, −0.01 to 1.67, P = 0.05), and pneumothorax (OR, 1.59; 95% CI, 0.98‐2.59, P = 0.06) after coronary artery bypass grafting compared with subjects without chronic obstructive pulmonary disease. The chronic obstructive pulmonary disease subjects had a significantly higher surgical site wound infection, respiratory failure, mortality, pneumonia, pleural effusion, stroke, and length of intensive care unit stay, and no significant difference in length of hospital stay, and pneumothorax after coronary artery bypass grafting compared with subjects without chronic obstructive pulmonary disease. The analysis of outcomes should be with caution because of the low sample size of 1 out of 11 studies in the meta‐analysis and a low number of studies in certain comparisons.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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