Effectiveness of enrofloxacin-alginate gel to prevent newborn calves' navels infection.

A trial was conducted with 414 newborn calves randomly divided by riskblocks of developing omphalitis or omphalophlebitis: low; medium, and high. The treatments were applied by stump-dipping daily for three days, with either iodine-polyvinylpyrrolidone (I-PVP) (n = 205), or with an alginate gel cont...

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Publicado en:Veterinaria México OA Vol. 9; pp. 1 - 13
Autores principales: Gutiérrez, Lilia, Rodríguez, Mariana, Rodríguez, Noe, Tapia, Graciela, Dominguez, Diana, Amigon, Miguel, Sumano, Héctor, Posadas-Manzano, Eduardo
Formato: Artículo
Publicado: Facultad de Medicina Veterinaria y Zootecnia UNAM 2022
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2022
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      pub: Facultad de Medicina Veterinaria y Zootecnia UNAM
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        10.22201/fmvz.24486760e.2022.1042
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        atl: Effectiveness of enrofloxacin-alginate gel to prevent newborn calves' navels infection.
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        au:
          Gutiérrez, Lilia
          Rodríguez, Mariana
          Rodríguez, Noe
          Tapia, Graciela
          Dominguez, Diana
          Amigon, Miguel
          Sumano, Héctor
          Posadas-Manzano, Eduardo
        affil:
          Universidad Nacional Autónoma de México, Facultad de Medicina Veterinaria y Zootecnia, Departamento de Fisiología y Farmacologia, Avenida Universidad 3000, Coyoacan, 04510, Ciudad de México
          Universidad Nacional Autónoma de México, Facultad de Medicina Veterinaria y Zootecnia, Departamento de Producción Animal-Rumiantes, Avenida Universidad 3000, Coyoacan, 04510, Ciudad de México
          Universidad Nacional Autónoma de México, Facultad de Medicina Veterinaria y Zootecnia, Departamento de Genética y Bioestadística, Avenida Universidad 3000, Coyoacan, 04510, Ciudad de México
          Benemérita Universidad Autónoma de Puebla, cuatro-Sur No. 104, Centro Histórico de Puebla, México
      su:
        Calves
        Navel
        Newborn infants
        Treatment failure
        Fluoroquinolones
        Alginates
      sug:
        subj:
          Calves
          Navel
          Newborn infants
          Treatment failure
          Fluoroquinolones
          Alginates
      keyword:
        calf
        enrofloxacin hydrochloride dehydrate
        navel
        omphaloflevitis
        preventive-treatment
      ab: A trial was conducted with 414 newborn calves randomly divided by riskblocks of developing omphalitis or omphalophlebitis: low; medium, and high. The treatments were applied by stump-dipping daily for three days, with either iodine-polyvinylpyrrolidone (I-PVP) (n = 205), or with an alginate gel containing 0.5 % enrofloxacin hydrochloride dehydrate (enro-C) (n = 209). Results showed that only one death occurred in the enro-C group, which was attributable to internal hemorrhage not linked with the treatment. After four days, we recorded six other cases as stump fibrosis, but these were inconsequential. In the I-PVP group, 44 calves developed cord infection and were considered treatment failures (13 high-risk; 11 medium-risk, and 20 low-risk) (P < 0.0435 in the three risk grades). The umbilical stump involution was evident in the enro-C-treated animals on day one as most stumps were noticeably dried. Stump detachment occurred within an average of nearly 30 days, and the umbilical scars did not present infection in any case. Conversely, in the remaining calves of the I-PVP group, stump drying was observable after 72 h, and it detached within an average of 32 days (P < 0.05). In stumps treated with enro-C, dirt stuck less, and the gel formed an apparently protecting layer around the umbilical scar when stump was either absent or too short. These results show that enro-C is a successful preventive treatment that allows rapid umbilical stump involution in newborn calves.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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