Associations between dairy fat intake, milk-derived free fatty acids, and cardiometabolic risk in Dutch adults.
Purpose: Milk-derived free fatty acids (FFAs) may act as both biomarkers of intake and metabolic effect. In this study we explored associations between different types of dairy consumption, a selection of milk-derived free fatty acids, and cardiometabolic disease (CMD) risk factors. Methods: Sixty-s...
| Published in: | European Journal of Nutrition Vol. 62; no. 1; pp. 185 - 199 |
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| Main Authors: | , , , , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Springer Nature
Feb2023
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=161689537&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 161689537 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14366207 CR0 jtl: European Journal of Nutrition issn: 14366207 maglogo: N pubinfo: dt: Feb2023 vid: 62 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 161689537 158359839 161689537 161689537 10.1007/s00394-022-02974-0 161689537 ppf: 185 ppct: 14 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Associations between dairy fat intake, milk-derived free fatty acids, and cardiometabolic risk in Dutch adults. aug: au: Li, Katherine J. Brouwer-Brolsma, Elske M. Fleuti, Charlotte Badertscher, René Vergères, Guy Feskens, Edith J. M. Burton-Pimentel, Kathryn J. affil: Division of Human Nutrition and Health, Department of Agrotechnology and Food Science, Wageningen University & Research, Wageningen, The Netherlands sug: subj: Dairy Products Dietary Fats Milk Fatty Acids Food Intake Evaluation Cardiometabolic Risk Factors In Adulthood Biological Markers Blood Risk Assessment Human Netherlands Adult Middle Age Chromatography, Gas Questionnaires Multiple Linear Regression Fatty Acids, Unsaturated Fatty Acids, Saturated Triglycerides Blood Lipoproteins, LDL Cholesterol Blood Funding Source Adult: 19-44 years Middle Aged: 45-64 years ab: Purpose: Milk-derived free fatty acids (FFAs) may act as both biomarkers of intake and metabolic effect. In this study we explored associations between different types of dairy consumption, a selection of milk-derived free fatty acids, and cardiometabolic disease (CMD) risk factors. Methods: Sixty-seven FFAs were quantified in the plasma of 131 free-living Dutch adults (median 60 years) using gas chromatography-flame ionization detector. Intakes of different dairy foods and groups were assessed using a food frequency questionnaire. Twelve different CMD risk factors were analyzed. Multiple linear regressions were used to evaluate the associations under study. Results: Based on the fully adjusted models, 5 long-chain unsaturated FFAs (C18:1 t13 + c6 + c7 + u, C18:2 c9t11 + u, C20:1 c11, C20:3 c8c11c14, and C20:4 c5c8c11c14), 2 medium-chain saturated FFAs (C15, C15 iso), and a trans FFA (C16:1 t9) were positively associated with at least one variable of dairy intake, as well as plasma total and LDL cholesterol, blood pressure, and SCORE (p ≤ 0.05). A long-chain PUFA associated with high-fat fermented dairy intake (C18:2 t9t12), was negatively associated with serum triglyceride levels, and a long-chain saturated FFA associated with cheese intake (C18:1 u1) was negatively associated with plasma LDL cholesterol and serum triglyceride levels. No clear associations were observed between dairy intake and CMD risk factors. Conclusion: Milk-derived FFAs could act as sensitive biomarkers for dairy intake and metabolism, allowing the association between dairy and CMD risk to be more precisely evaluated. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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