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Comparison of Corneal Densitometry and Visual Quality after Small Incision Lenticule Extraction (SMILE) and Laser Epithelial Keratomileusis (LASEK): One-Year Comparative Study.

Purpose. To investigate changes in corneal densitometry (CD) and visual quality following small incision lenticule extraction (SMILE) and laser epithelial keratomileusis (LASEK) in patients with mild-to-moderate myopia. Methods. A retrospective analysis was performed on 24 and 25 patients (46 eyes e...

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Published in:BioMed Research International Vol. 2023; pp. 1 - 12
Main Authors: Cai, Wenting, Liu, Lin, Li, Min, Shi, Yuehui, Sun, Lina, Ma, Xiaoyun, Zou, Jun
Format: research tables/charts Journal Article
Published: Wiley-Blackwell 2/2/2023
Online Access:View this record in EBSCOhost
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        23146133
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      jtl: BioMed Research International
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      dt: 2/2/2023
      vid: 2023
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        161719529
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        10.1155/2023/3430742
        161719529
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        atl: Comparison of Corneal Densitometry and Visual Quality after Small Incision Lenticule Extraction (SMILE) and Laser Epithelial Keratomileusis (LASEK): One-Year Comparative Study.
      aug:
        au:
          Cai, Wenting
          Liu, Lin
          Li, Min
          Shi, Yuehui
          Sun, Lina
          Ma, Xiaoyun
          Zou, Jun
        affil: Department of Ophthalmology, Shanghai Tenth People's Hospital, Tongji University, Shanghai 200072, China
      sug:
        subj:
          Corneal Diseases Diagnosis
          Densitometry
          Visual Acuity Evaluation
          Myopia Surgery
          Laser Therapy
          Keratomileusis, Laser in Situ
          Small-Incision Lenticule Extraction
          Time Factors
          Epithelium Surgery
          Keratectomy, Subepithelial, Laser-Assisted
          Comparative Studies
          Retrospective Design
          Patient Safety
          Drug Efficacy
          Correlational Studies
          Treatment Outcomes
          Human
          Male
          Female
          Young Adult
          Adult
          Data Analysis Software
          Descriptive Statistics
          Adult: 19-44 years
          Male
          Female
      ab: Purpose. To investigate changes in corneal densitometry (CD) and visual quality following small incision lenticule extraction (SMILE) and laser epithelial keratomileusis (LASEK) in patients with mild-to-moderate myopia. Methods. A retrospective analysis was performed on 24 and 25 patients (46 eyes each) who underwent SMILE and LASEK, respectively, for mild-to-moderate myopia. The visual quality and CD values were recorded. Using the Pentacam Scheimpflug system, CD values were collected in three concentric optical zones at the depths of the anterior, central, and posterior layers. Efficacy, safety, predictability, corneal wavefront aberrations, and QoV scores were measured to evaluate visual quality. A correlation analysis was performed between changes in CD and clinical characteristics. Results. There were no statistical differences in efficacy and safety indices between the two groups. At 3 months postoperatively, a pronounced reduction in several zones was observed in the LASEK group (p < 0.05), whereas no obvious change was observed in the SMILE group. There were obvious changes in the CD values in several zones in the SMILE and LASEK groups (p < 0.05) after 1 year. The magnitude of the CD changes in the anterior and central corneal layers was smaller in the SMILE group than in the LASEK group (all p < 0.05). Lower HOAs, spherical aberration, and horizontal comas of the anterior and whole corneal surfaces were observed in the SMILE group. QoV scores were similar between the two groups. Conclusion. CD decreased in the SMILE and LASEK groups after 1 year; there was a smaller reduction in SMILE than in LASEK. SMILE and LASEK did not differ significantly in terms of safety and effectiveness in correcting mild-to-moderate myopia.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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