Early life factors and hippocampal functional connectivity in children with overweight/obesity.
Summary: Objective: We investigated the association of anthropometric neonatal data (birth length and birth weight) and breastfeeding practices (exclusive and any breastfeeding) with hippocampal functional connectivity and its academic implication in children with overweight/obesity. Methods: Ninety...
| Publicado en: | Pediatric Obesity Vol. 18; no. 3; pp. 1 - 11 |
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| Autores principales: | , , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Mar2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=161724342&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 161724342 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 20476302 ETV7 jtl: Pediatric Obesity issn: 20476302 maglogo: Y pubinfo: dt: Mar2023 vid: 18 iid: 3 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 161724342 160972244 161724342 161724342 10.1111/ijpo.12998 161724342 ppf: 1 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Early life factors and hippocampal functional connectivity in children with overweight/obesity. aug: au: Solis‐Urra, Patricio Esteban‐Cornejo, Irene Mora‐Gonzalez, Jose Stillman, Chelsea Contreras‐Rodriguez, Oren Erickson, Kirk I. Catena, Andrés Ortega, Francisco B. affil: PROFITH "PROmoting FITness and Health Through Physical Activity" Research Group, Sport and Health University Research Institute (iMUDS), Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, Granada, Spain sug: subj: Pediatric Obesity Functional Connectivity In Infancy and Childhood Birth Weight Body Height Breast Feeding Hippocampus Physiology Human Funding Source Child Infant Cross Sectional Studies Anthropometry Descriptive Statistics Academic Performance Post Hoc Analysis Regression Magnetic Resonance Imaging Child: 6-12 years Infant: 1-23 months ab: Summary: Objective: We investigated the association of anthropometric neonatal data (birth length and birth weight) and breastfeeding practices (exclusive and any breastfeeding) with hippocampal functional connectivity and its academic implication in children with overweight/obesity. Methods: Ninety six children with overweight/obesity aged 8–11 years (10.01 ± 1.14), from the ActiveBrains project were included in this cross‐sectional study. Anthropometric neonatal data were collected from birth records, whereas breastfeeding practices were reported by parents. A 3.0 Tesla Siemens Magnetom Tim Trio system was used to acquire T1‐weighted and resting‐state functional magnetic resonance images. Academic performance was assessed by the Woodcock‐Muñoz standardized test. Hippocampal seed‐based methods with post‐hoc regression analyses were performed. Analyses were considered significant when surpassing Family‐Wise Error corrections. Results: Birth weight showed a positive association with the connectivity between the hippocampus and the pre‐ and postcentral gyri, and the cerebellum. In addition, breastfeeding was negatively associated with the connectivity between the hippocampus and the primary motor cortex and the angular gyrus. Any breastfeeding, in turn, showed a positive association with the connectivity between the hippocampus and the middle temporal gyrus. None of the connectivity outcomes related to early life factors was coupled with better academic abilities (all p > 0.05). Conclusions: Our findings suggest that birth weight at birth and breastfeeding are associated with hippocampal connectivity in children with overweight/obesity. Despite this, how the results relate to academic performance remains a matter of speculation. Our findings suggest that clinicians should recognize the importance early life factors for potentially avoiding consequences on offspring's brain development. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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