Motivation and family communication in hereditary prostate cancer genetic testing: Survey of patients from a US tertiary medical center.

Identification of a hereditary prostate cancer in an affected individual can guide treatment and may also impact cancer screening and surveillance for patients and their relatives. This study aimed to determine the factors that are associated with the decision‐making process of individuals with pros...

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Published in:Journal of Genetic Counseling Vol. 32; no. 1; pp. 79 - 90
Main Authors: Finn, Caitlin M., McCormick, Shelley, Peterson, Danielle, Niendorf, Kristin B., Rodgers, Linda H.
Format: research tables/charts Journal Article
Published: Wiley-Blackwell Feb2023
Online Access:View this record in EBSCOhost
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      dt: Feb2023
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1002/jgc4.1624
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        atl: Motivation and family communication in hereditary prostate cancer genetic testing: Survey of patients from a US tertiary medical center.
      aug:
        au:
          Finn, Caitlin M.
          McCormick, Shelley
          Peterson, Danielle
          Niendorf, Kristin B.
          Rodgers, Linda H.
        affil: MGH Institute of Health Professions Genetic Counseling Program, Boston Massachusetts,, USA
      sug:
        subj:
          Prostatic Neoplasms Familial and Genetic
          Hereditary Diseases
          Genetic Screening
          Decision Making, Patient Evaluation
          Motivation
          Communication
          Family Relations
          Human
          Descriptive Statistics
          Data Analysis Software
          Tertiary Health Care United States
          United States
          Genetic Counseling
          Family History
          Descriptive Research
          Comparative Studies
          Male
          Female
          Adult
          Middle Age
          Aged
          Aged, 80 and Over
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Identification of a hereditary prostate cancer in an affected individual can guide treatment and may also impact cancer screening and surveillance for patients and their relatives. This study aimed to determine the factors that are associated with the decision‐making process of individuals with prostate cancer regarding whether to pursue genetic testing as well as how, why, and with whom genetic test results are shared. We surveyed 113 patients diagnosed with prostate cancer who received cancer genetic counseling through a United States tertiary medical center, inquiring about genetic testing motivations and family communication about results. Among those who pursued genetic testing, (1) learning about my family's possible cancer risk (98%), (2) learning information that may guide cancer treatment (93%), and (3) learning if I am at risk for future cancers (92%) were most frequently identified as slightly or very important factors in their decision. Participants shared their genetic test results in a higher proportion to male first‐degree relatives than female first‐degree relatives; however, no significant difference was found (p = 0.103). Our study may suggest sex differences related to family communication about genetic testing results. Such findings indicate a critical need for genetic counselors to clearly communicate the impact of genetic test results on both male and female relatives. Further research on motivation and family communication about genetic test results in diverse cohorts is needed.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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