Associations between Circumstances Surrounding Overdose and Underlying Classes of Polysubstance Overdose Deaths.

The overdose crisis is worsening, with polysubstance overdose deaths involving psychostimulants increasing in the U.S. Substance-specific prevention and intervention activities may not be as effective for polysubstance use, so we sought to classify substances used among overdose decedents to identif...

Descripción completa

Detalles Bibliográficos
Publicado en:Substance Use & Misuse Vol. 58; no. 3; pp. 434 - 444
Autores principales: Thomas, Shawn A., Wagner, Karla D., Clements-Nolle, Kristen D., Omaye, Stanley, Lu, Minggen, Yang, Wei
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd 2023
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=161761430&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 161761430
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        10826084
        2VI
      jtl: Substance Use & Misuse
      issn: 10826084
      maglogo: Y
    pubinfo:
      dt: 2023
      vid: 58
      iid: 3
      pid: 377
      pub: Taylor & Francis Ltd
      place: Philadelphia, Pennsylvania
    artinfo:
      ui:
        161761430
        161177285
        161761430
        161761430
        10.1080/10826084.2023.2165414
        161761430
      ppf: 434
      ppct: 10
      formats:
      tig:
        atl: Associations between Circumstances Surrounding Overdose and Underlying Classes of Polysubstance Overdose Deaths.
      aug:
        au:
          Thomas, Shawn A.
          Wagner, Karla D.
          Clements-Nolle, Kristen D.
          Omaye, Stanley
          Lu, Minggen
          Yang, Wei
        affil: School of Public Health, University of Nevada, Reno, Reno, Nevada, USA
      sug:
        subj:
          Substance Abuse Mortality
          Overdose Mortality
          Central Nervous System Stimulants
          Analgesics, Opioid
          Human
          Death Certificates
          Descriptive Statistics
          Chi Square Test
          Forensic Toxicology
          Structural Equation Modeling
          Logistic Regression
          Drugs, Prescription
          Methamphetamine
          Comparative Studies
          Odds Ratio
          Overdose Prevention and Control
          Harm Reduction
          Funding Source
          Nevada
          Female
          Male
          Female
          Male
      ab: The overdose crisis is worsening, with polysubstance overdose deaths involving psychostimulants increasing in the U.S. Substance-specific prevention and intervention activities may not be as effective for polysubstance use, so we sought to classify substances used among overdose decedents to identify unique factors related to these classes. We used data from the Nevada State Unintentional Drug Overdose Reporting System, Jan 2019–Jun 2021, which comes from death certificates, coroner/medical examiner reports, and postmortem toxicology. Latent class analysis, multinomial logistic regression, and Chi-squared tests determined underlying drug use classes, differences in characteristics and circumstances surrounding overdose, and assessed relationships between circumstances and drug use classes. We identified four latent classes: (1) prescription drugs (19.1%), (2) predominately methamphetamine (31.4%), (3) multi-drug (28.9%), and (4) opioid and stimulant (20.6%). Compared to other classes, the prescription drug class had a higher percentage of female decedents, from rural counties, with mental health diagnoses, who died at home. The predominately methamphetamine class had a higher percentage of decedents experiencing homelessness. The multi-drug use class had higher percentage of younger and Hispanic decedents. Those in the opioid and stimulant class had higher odds of being recently released from an institutional setting, compared to the multi drug class. These underlying classes were associated with several characteristics and circumstances that can prove useful for prevention, treatment, and harm reduction agencies when designing programs and interventions to target specific groups of people at-risk for drug overdose.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N