Clinical correlates of suicidality and self-injurious behaviour among Canadian adolescents with bipolar disorder.
There is high risk of suicidality in bipolar disorder (BD), particularly in early onset cases. The literature regarding correlates and putative predictors of suicide attempts (SA), non-suicidal self-injury (NSSI) and suicidal ideation (SI) among youth with BD remains sparse. Participants included 19...
| Published in: | European Child & Adolescent Psychiatry Vol. 32; no. 1; pp. 41 - 52 |
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| Main Authors: | , , , , , , , |
| Format: | research tables/charts Journal Article |
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Springer Nature
Jan2023
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=161768885&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 161768885 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10188827 EJ3 jtl: European Child & Adolescent Psychiatry issn: 10188827 maglogo: N pubinfo: dt: Jan2023 vid: 32 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 161768885 150463782 161768885 161768885 10.1007/s00787-021-01803-9 161768885 ppf: 41 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Clinical correlates of suicidality and self-injurious behaviour among Canadian adolescents with bipolar disorder. aug: au: Khoubaeva, Diana Dimick, Mikaela Timmins, Vanessa H. Fiksenbaum, Lisa M. Mitchell, Rachel H. B. Schaffer, Ayal Sinyor, Mark Goldstein, Benjamin I. affil: Centre for Youth Bipolar Disorder, Centre for Addiction and Mental Health, 80 Workman Way, M6J 1H4, Toronto, ON, Canada sug: subj: Suicidal Ideation Risk Factors Self-Injurious Behavior Risk Factors Bipolar Disorder Canada Risk Assessment Human Cross Sectional Studies Retrospective Design Canada Semi-Structured Interview Adolescence Univariate Statistics Descriptive Statistics Multiple Regression Odds Ratio Sex Factors Emotional Regulation Depression Complications Mental Disorders Complications Hospitalization Tertiary Health Care Male Female Adolescent: 13-18 years Male Female ab: There is high risk of suicidality in bipolar disorder (BD), particularly in early onset cases. The literature regarding correlates and putative predictors of suicide attempts (SA), non-suicidal self-injury (NSSI) and suicidal ideation (SI) among youth with BD remains sparse. Participants included 197 adolescents with BD, divided into 4 groups: SA (with or without NSSI), NSSI (with or without SI), SI only, and comparison group (CG; no SA/NSSI/SI). Diagnoses, treatment, and suicidality measures were determined via semi-structured interviews, conducted between 2009 and 2017. Univariate analyses were followed by multinomial regression. Overall, 73.6% of participants had history of SA, NSSI, and/or SI. In comparison to CG, SA and NSSI were each associated with BD-II/-NOS (odds ratio [OR] = 15.99, p = 0.002; OR = 16.76, p = 0.003), female sex (OR = 6.89, p = 0.006; OR = 3.76, p = 0.02), and emotion dysregulation (OR = 1.10, p < 0.001; OR = 1.07, p = 0.004). NSSI and SI were each associated with most severe lifetime depression (OR = 1.10, p = 0.01; OR = 1.10, p = 0.01). SA and SI were associated with psychiatric hospitalization (OR = 19.45, p = 0.001; OR = 6.09, p = 0.03). SA was associated with poorer global functioning at most severe episode (OR = 0.88, p = 0.008). NSSI was associated with not living with both natural parents (OR = 0.22, p = 0.009). Study limitations include cross-sectional and retrospective design, stringent cut-offs for SA and NSSI, and recruitment from a tertiary clinical setting. Three quarters of adolescents with BD have had suicidality and/or self-injury. SA and NSSI were most similar to one another, and most different from CG, supporting the broader construct of self-harm. Future research should address the gap in knowledge regarding how sex differences and neurobiology are associated with the observed clinical differences. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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