Parental rejection in early adolescence predicts a persistent ADHD symptom trajectory across adolescence.

Despite a general decrease of attention-deficit/hyperactivity disorder (ADHD) symptoms during adolescence, these may persist in some individuals but not in others. Prior cross-sectional studies have shown that parenting style and their interaction with candidate genes are associated with ADHD sympto...

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Published in:European Child & Adolescent Psychiatry Vol. 32; no. 1; pp. 139 - 154
Main Authors: Brinksma, Djûke M., Hoekstra, Pieter J., de Bildt, Annelies, Buitelaar, Jan K., van den Hoofdakker, Barbara J., Hartman, Catharina A., Dietrich, Andrea
Format: research tables/charts Journal Article
Published: Springer Nature Jan2023
Online Access:View this record in EBSCOhost
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      dt: Jan2023
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00787-021-01844-0
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        atl: Parental rejection in early adolescence predicts a persistent ADHD symptom trajectory across adolescence.
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        au:
          Brinksma, Djûke M.
          Hoekstra, Pieter J.
          de Bildt, Annelies
          Buitelaar, Jan K.
          van den Hoofdakker, Barbara J.
          Hartman, Catharina A.
          Dietrich, Andrea
        affil: Department of Child and Adolescent Psychiatry, University Medical Center Groningen, University of Groningen, Lübeckweg 2, NL-9723 HE, Groningen, The Netherlands
      sug:
        subj:
          Parent-Child Relations
          Parenting
          Genotype
          Attention Deficit Hyperactivity Disorder Risk Factors
          Risk Assessment
          Human
          Odds Ratio
          Child
          Adolescence
          Male
          Female
          Child: 6-12 years
          Adolescent: 13-18 years
          Male
          Female
      ab: Despite a general decrease of attention-deficit/hyperactivity disorder (ADHD) symptoms during adolescence, these may persist in some individuals but not in others. Prior cross-sectional studies have shown that parenting style and their interaction with candidate genes are associated with ADHD symptoms. However, there is a lack of longitudinal research examining the independent and interactive effects of parenting and plasticity genes in predicting the course of attention-deficit/hyperactivity disorder (ADHD) symptoms across adolescence. Here, we investigated how children perceived their parents' parenting style (i.e., rejection, overprotection, and emotional warmth) at the age of 11, and their interaction with DRD4,MAOA, and 5-HTTLPR genotypes on parent-reported ADHD symptoms at three time points (mean ages 11.1, 13.4, and 16.2 years) in 1730 adolescents from the TRacking Adolescents' Individual Lives Survey (TRAILS). Growth Mixture Modeling in Mplus identified four ADHD symptom trajectories: low, moderate stable, high decreasing, and high persistent. Perceived parental rejection predicted class membership in the high persistent trajectory compared to the other classes (p < 0.001, odds ratios between 2.14 and 3.74). Gene-environment interactions were not significantly related to class membership. Our results indicate a role of perceived parental rejection in the persistence of ADHD symptoms. Perceived parental rejection should, therefore, be taken into consideration during prevention and treatment of ADHD in young adolescents.
      pubtype: Academic Journal
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        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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