Cognition and Suicide Risk Among Individuals With First-Episode Psychosis: A 6-Month Follow-Up.

Objective: There is emerging evidence that greater cognition is associated with increased risk for suicide among individuals with psychosis. Given this association, concerns have been raised that cognitive interventions might actually increase risk for suicide in this population. Therefore, the pres...

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Publicado en:Psychiatric Rehabilitation Journal Vol. 45; no. 1; pp. 27 - 34
Autores principales: Wastler, Heather M., Moe, Aubrey M., Pine, Jacob G., Breitborde, Nicholas J. K.
Formato: research tables/charts Journal Article
Publicado: American Psychological Association Mar2022
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: Psychiatric Rehabilitation Journal
      issn: 1095158X
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      dt: Mar2022
      vid: 45
      iid: 1
      pid: 34
      pub: American Psychological Association
      place: Washington, District of Columbia
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        10.1037/prj0000488
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        atl: Cognition and Suicide Risk Among Individuals With First-Episode Psychosis: A 6-Month Follow-Up.
      aug:
        au:
          Wastler, Heather M.
          Moe, Aubrey M.
          Pine, Jacob G.
          Breitborde, Nicholas J. K.
        affil: Department of Psychiatry and Behavioral Health, The Ohio State University
      sug:
        subj:
          Cognition
          Suicide Risk Factors
          Risk Assessment
          Psychotic Disorders
          Human
          Male
          Female
          Adult
          Scales
          Cross Sectional Studies
          Prospective Studies
          Mediation Analysis
          Depression
          Descriptive Statistics
          Confidence Intervals
          Funding Source
          Adult: 19-44 years
          Male
          Female
      ab: Objective: There is emerging evidence that greater cognition is associated with increased risk for suicide among individuals with psychosis. Given this association, concerns have been raised that cognitive interventions might actually increase risk for suicide in this population. Therefore, the present study investigated the cross-sectional and longitudinal relationship between cognition and suicide risk among individuals with first-episode psychosis. Method: Sixty-five participants completed measures of suicide risk, depression, and cognition at baseline and 6 months. Within-subject mediation analysis was used to examine the indirect effect of cognition on suicide risk. Within-subject moderation analysis was used to examine whether participation in cognitive enhancing intervention (e.g., computerized drill-and-practice cognitive remediation and metacognitive remediation therapy) moderated changes in suicide risk. Results: Consistent with prior studies, our cross-sectional results suggest that greater cognition is associated with increased risk for suicide. However, this effect was limited in scope, as we found that verbal learning was the only cognitive domain associated with suicide risk in our sample. Results from our longitudinal analyses show that changes in depressive symptoms, but not changes verbal learning, mediate changes in suicide risk during the first 6 months of treatment. In addition, participation in cognitive enhancing interventions did not moderate changes in suicide risk. Conclusions and Implications for Practice: Our results suggest that cognition is a correlate, or a proxy risk factor, rather than a causal risk factor for suicide. Although these findings contradict previously raised concerns that cognitive interventions might unintentionally increase risk for suicide, ongoing assessment is warranted and additional research is needed. Impact and Implications: The present study showed that better verbal learning was associated with suicide risk at baseline, though changes in verbal learning did not lead to changes in suicide risk during the first 6 months of treatment. In addition, treatments that improve cognition did not increase suicide risk. These findings indicate that cognition does not have a causal impact on suicide risk. These findings also alleviate previously raised concerns that cognitive enhancing treatments might inadvertently increase suicide risk. Overall, our findings support the continued use of cognitive enhancing interventions to assist patients in reaching their personal recovery goals.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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