Inhibition of Motor Planning and Response Selection after Anterior Cruciate Ligament Reconstruction.

Purpose: The purpose of this study is to compare cortical motor planning activity during response selection and motor execution processes between individuals with anterior cruciate ligament reconstruction (ACLR) and uninjured controls during a reaction time and response selection task. Methods: Indi...

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Publicado en:Medicine & Science in Sports & Exercise Vol. 55; no. 3; pp. 440 - 450
Autores principales: SHERMAN, DAVID A., BAUMEISTER, JOCHEN, STOCK, MATT S., MURRAY, AMANDA M., BAZETT-JONES, DAVID M., NORTE, GRANT E.
Formato: pictorial research tables/charts Journal Article
Publicado: Lippincott Williams & Wilkins Mar2023
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: Medicine & Science in Sports & Exercise
      issn: 01959131
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    pubinfo:
      dt: Mar2023
      vid: 55
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      pid: 433
      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
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        10.1249/MSS.0000000000003072
        161868920
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        atl: Inhibition of Motor Planning and Response Selection after Anterior Cruciate Ligament Reconstruction.
      aug:
        au:
          SHERMAN, DAVID A.
          BAUMEISTER, JOCHEN
          STOCK, MATT S.
          MURRAY, AMANDA M.
          BAZETT-JONES, DAVID M.
          NORTE, GRANT E.
        affil: Live4 Physical Therapy and Wellness, Acton, MA
      sug:
        subj:
          Anterior Cruciate Ligament Injuries Surgery
          Anterior Cruciate Ligament Reconstruction Methods
          Motor Skills
          Reaction Time
          Task Performance and Analysis
          Evoked Potentials
          Human
          Male
          Female
          Young Adult
          Cross Sectional Studies
          Power Analysis
          Analysis of Variance
          Confidence Intervals
          Pearson's Correlation Coefficient
          Data Analysis Software
          Descriptive Statistics
          Transcranial Magnetic Stimulation
          Electroencephalography
          Male
          Female
      ab: Purpose: The purpose of this study is to compare cortical motor planning activity during response selection and motor execution processes between individuals with anterior cruciate ligament reconstruction (ACLR) and uninjured controls during a reaction time and response selection task. Methods: Individuals with ACLR (n = 20) and controls (n = 20) performed a lateralized choice reaction time (e.g., Go/NoGo) task. Electrocortical activity and reaction time were recorded concurrently using electroencephalography and inertial measurement units. Separate stimulus locked and response-locked event-related potentials were computed for each limb. The lateralized readiness potential (LRP) was computed as the interhemispheric differences between waveforms and the mean LRP area and onset latency were recorded. Active motor threshold was determined using transcranial magnetic stimulation. Differences between groups (ACLR vs control) and limbs (involved vs uninvolved) and the associations between LRP characteristics and response performance (number of errors) were assessed. Results: Participants with ACLR have had smaller LRP area during periods of response selection (P = 0.043, d = 0.4) and motor execution (P = 0.015, d = 0.5) and committed more errors in both Go (P < 0.001, d = 0.8) and NoGo (P = 0.032, d = 0.5) response conditions. There were no differences in latency of response selection or motor execution. Participants with ACLR had higher active motor thresholds (P < 0.001, d = 1.3) than controls, which was weakly associated with smaller LRP areas (r = 0.32–0.42, P < 0.05). Conclusions: The ACLR group demonstrated greater motor planning and response inhibition during a choice reaction time task. More errant performance also suggests poorer decision making in the presence of a "speed-accuracy" trade-off. Key features of the sample, including lower corticospinal excitability, lend support to an interpretation of widespread cortical inhibition contributing to impairments in response selection and motor execution.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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