Evolving Therapeutic Scenario of Stage III Non-Small-Cell Lung Cancer.

Lung cancer remains the leading cause of cancer-related death with an incidence that continues to increase in both sexes and all ages. However, 80% to 90% of lung cancers are non-small cell lung cancer (NSCLC) and the remaining 10% to 20% are small cell lung cancer. Adenocarcinoma is the most common...

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Publicado en:Clinical Medicine Insights: Oncology pp. 1 - 11
Autores principales: Baudoux, Nathalie, Friedlaender, Alex, Addeo, Alfredo
Formato: algorithm research tables/charts Journal Article
Publicado: Sage Publications Inc. 2/14/2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2/14/2023
      pid: 344
      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        atl: Evolving Therapeutic Scenario of Stage III Non-Small-Cell Lung Cancer.
      aug:
        au:
          Baudoux, Nathalie
          Friedlaender, Alex
          Addeo, Alfredo
        affil: Oncology Department, Geneva University Hospitals, Geneva, Switzerland
      sug:
        subj:
          Carcinoma, Non-Small-Cell Lung
          Human
          Descriptive Statistics
          Multidisciplinary Care Team
          Chemotherapy, Cancer
          Radiotherapy
          Immunotherapy
          Lung Neoplasms
          Adenocarcinoma
      ab: Lung cancer remains the leading cause of cancer-related death with an incidence that continues to increase in both sexes and all ages. However, 80% to 90% of lung cancers are non-small cell lung cancer (NSCLC) and the remaining 10% to 20% are small cell lung cancer. Adenocarcinoma is the most common histologic subtype of lung cancer worldwide. More frequently, lung cancer diagnosis is made in advanced stages. Stage III NSCLC refers to locoregionally advanced disease without metastases and represents about 30% NSCLC cases. Despite the absence of metastases at diagnosis, the outcome is generally poor. Stage III comprises a heterogeneous group and optimal management requires the input of a multidisciplinary team. All modalities of oncologic treatment are involved: surgery, chemotherapy, radiotherapy, and more recently, immunotherapy and targeted therapy. We will discuss the different therapeutic options in stage III NSCLC, both in operable and inoperable scenarios, and the role of immunotherapy and targeted therapy.
      pubtype: Academic Journal
      doctype:
        algorithm
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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