Comparison of liver iron concentration calculated from R2* at 1.5 T and 3 T.
Purpose: R2*, a measurement obtained using magnetic resonance imaging (MRI) can be used to estimate liver iron concentration (LIC). 3 T and 1.5 T scanners can be used but conversion of 3 T R2* to LIC is less well validated. In this study the aim was to compare 3 T-R2* LIC and 1.5 T-R2* LIC estimatio...
| Publicado en: | Abdominal Radiology Vol. 48; no. 3; pp. 865 - 874 |
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| Autores principales: | , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Mar2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=161991646&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 161991646 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 2366004X JT14 jtl: Abdominal Radiology issn: 2366004X maglogo: N pubinfo: dt: Mar2023 vid: 48 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 161991646 160800070 10.1007/s00261-022-03762-4 161991646 ppf: 865 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Comparison of liver iron concentration calculated from R2* at 1.5 T and 3 T. aug: au: Pickles, Elisabeth Kumar, Shravan Brady, Michael Telford, Alison Pavlides, Michael Bulte, Daniel affil: Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Old Road Campus Research Building, OX3 7DQ, Headington, Oxford, UK sug: ab: Purpose: R2*, a measurement obtained using magnetic resonance imaging (MRI) can be used to estimate liver iron concentration (LIC). 3 T and 1.5 T scanners can be used but conversion of 3 T R2* to LIC is less well validated. In this study the aim was to compare 3 T-R2* LIC and 1.5 T-R2* LIC estimations to assess if they can be used interchangeably. Methods: Thirty participants were scanned at both 1.5 T and 3 T. R2* was measured at both field strengths. 3 T R2* and 1.5 R2* were compared using linear regression and were converted to LIC using different calibration curves. Pearson's rho and Intraclass Correlation Coefficients (ICCs) were used to assess correlation and agreement between 1.5 and 3 T LIC. Bland Altman plots were used to assess bias and limits of agreement. Results: All 1.5 T and 3 T LIC comparisons gave Pearson's rho of 0.99 (p < 0.001). ICC ranged from 0.83 (p = 0.005) to 0.96 (p < 0.001). Biases had magnitude of less than 0.2 mg/g dry weight. Conclusion: Agreement and bias between 3 and 1.5 T-R2* LIC depended on the method used for conversion. There were instances when the agreement was excellent and bias was small, indicating that potentially 3 T-R2* LIC can be used alongside or instead of 1.5 T-R2* LIC but care needs to be taken over the conversion methods selected. Trial registration number: Clinicaltrials.gov NCT03743272, 16 November 2018. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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