A Preliminary Investigation into the Neural Correlates of Knee Loading during a Change of Direction Task in Individuals after Anterior Cruciate Ligament Reconstruction.

Background Central nervous system (CNS) function after ACLR, quantified by the blood oxygen level dependent (BOLD) response, is altered in regions of sensory function during knee movement after ACLR. However, it is unknown how this altered neural response may manifest in knee loading and response to...

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Published in:International Journal of Sports Physical Therapy Vol. 18; no. 1; pp. 70 - 81
Main Authors: Culiver, Adam, Grooms, Dustin, Edwards, Nathan, Schmitt, Laura, Oñate, James
Format: pictorial research tables/charts Journal Article
Published: North American Journal of Sports Physical Therapy 2023
Online Access:View this record in EBSCOhost
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      dt: 2023
      vid: 18
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      pub: North American Journal of Sports Physical Therapy
      place: Indianapolis, Indiana
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        10.26603/001c.57782
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        atl: A Preliminary Investigation into the Neural Correlates of Knee Loading during a Change of Direction Task in Individuals after Anterior Cruciate Ligament Reconstruction.
      aug:
        au:
          Culiver, Adam
          Grooms, Dustin
          Edwards, Nathan
          Schmitt, Laura
          Oñate, James
        affil: School of Health and Rehabilitation Sciences, Ohio State University
      sug:
        subj:
          Anterior Cruciate Ligament Reconstruction
          Task Performance and Analysis
          Central Nervous System Physiology
          Lower Extremity Physiology
          Kinetics
          Human
          Male
          Female
          Adolescence
          Young Adult
          Motion Capture
          Adolescent: 13-18 years
          Male
          Female
      ab: Background Central nervous system (CNS) function after ACLR, quantified by the blood oxygen level dependent (BOLD) response, is altered in regions of sensory function during knee movement after ACLR. However, it is unknown how this altered neural response may manifest in knee loading and response to sensory perturbations during sport specific movements. Purpose To investigate the relationship among CNS function and lower extremity kinetics, under multiple visual conditions, during 180° change of direction task in individuals with a history of ACLR. Methods Eight participants, 39.3 ± 37.1 months after primary, left ACLR performed repetitive active knee flexion and extension of their involved knee during fMRI scanning. Participants separately performed 3D motion capture analysis of a 180° change of direction task under full vision (FV) and stroboscopic vision (SV) conditions. A neural correlate analysis was performed to associate BOLD signal to knee loading of the left lower extremity. Results Involved limb peak internal knee extension moment (pKEM) was significantly lower in the SV condition (1.89 ± 0.37 N*m/Kg) compared to the FV condition (2.0 ± 0.34 N*m/Kg) (p = .018). Involved limb pKEM during the SV condition was positively correlated with BOLD signal in the contralateral precuneus and superior parietal lobe (Voxels: 53; p = .017; z-stat max: 6.47; MNI peak: 6, -50, 66). Conclusion There is a positive association between involved limb pKEM in the SV condition and BOLD response in areas of visual-sensory integration. Activation of contralateral precuneus and superior parietal lobe brain regions may be a strategy to maintain joint loading when vision is perturbed. Level of Evidence Level 3
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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