PHILIPPE HENRI ARNOUT DE CLERMONT: Organophosphates, ethers, phenols, and other organic subjects.
Philippe de Clermont (1831–1921) was a French organic chemist, known particularly for his synthesis of tetraethyl pyrophosphate, the first organophosphate cholinesterase inhibitor. This achievement was part of an extensive research about phosphoric ethers using Wurtz’s procedure. This type of synthe...
| Publicado en: | Revista CENIC Ciencias Quimicas no. 2; pp. 335 - 351 |
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| Formato: | Artículo |
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Centro Nacional de Investigaciones Cientificas
jul-dic2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=lth&AN=162096260&site=ehost-live header: @attributes: shortDbName: lth uiTerm: 162096260 longDbName: MedicLatina uiTag: AN controlInfo: bkinfo: jinfo: jid: 10158553 UF0 jtl: Revista CENIC Ciencias Quimicas issn: 10158553 maglogo: N pubinfo: dt: jul-dic2022 iid: 2 pid: 21205 pub: Centro Nacional de Investigaciones Cientificas artinfo: ui: 162096260 ppf: 335 ppct: 16 formats: fmt: @attributes: type: P size: 1.5MB tig: atl: PHILIPPE HENRI ARNOUT DE CLERMONT: Organophosphates, ethers, phenols, and other organic subjects. aug: au: Wisniak, Jaime affil: Department of Chemical Engineering, Ben-Gurion University of the Negev,Beer-Sheva, Israel 84105. su: Arnout de Clermont, Philippe Henri Metal sulfides Pyruvic acid Octene Pyrogallic acid Chemical decomposition Cholinesterase reactivators Cholinesterase inhibitors Pyrophosphates Phenols Thiourea Ethers Manganous sulfide Ammonium chloride sug: subj: Arnout de Clermont, Philippe Henri Metal sulfides Pyruvic acid Octene Pyrogallic acid Chemical decomposition Cholinesterase reactivators Cholinesterase inhibitors Pyrophosphates Phenols Thiourea Ethers Manganous sulfide Ammonium chloride keyword: aurin metal sulfides phenols phosphorous ethers pyrogallic acid tetraethyl pyrophosphate ácido pirogálico éteres fosfóricos aurina fenoles sulfuros metálicos tetra etil pirofosfato ab: Philippe de Clermont (1831–1921) was a French organic chemist, known particularly for his synthesis of tetraethyl pyrophosphate, the first organophosphate cholinesterase inhibitor. This achievement was part of an extensive research about phosphoric ethers using Wurtz’s procedure. This type of synthesis was found to be also appropriate for the preparation of carbonic ethers. Another important consequence was that the reaction between ammonia and an ether composed of a mineral oxacid resulted in the formation of an alcoholic alkali. Clermont also carried extensive research about octene and its derivatives that culminated in the synthesis of a large number of new derivatives, among them octylene oxide acetate, caprylene halides and alcohol, octyl glycol, octyl glycol chlorhydrin, etc. Clermont determined the composition of persulfonic acid, synthesized sulfophenylurea, and a variety of thioureas. He also studied a variety of reactions of pyruvic acid, the composition of pyrogallic acid, synthesized purpurogallin, and a variety of metallic sulfides, in particularly the flesh and green sulfides of manganese and the decomposition reaction of ammonium chloride with metallic sulfides. Likewise, he showed that the production of aurin required the presence of nascent CO. Philippe de Clermont (1831–1921) fue in químico francés, conocido particularmente por su síntesis del tetra etilo pirofosfato, el primer inhibidor del orgánofosfato colinesterasa. Este logro fue parte de un programa extenso acerca éteres fosfóricos usando el procedimiento de Würtz. Este tipo de síntesis probó ser también apropiado para la preparación de éteres carbónicos. Otro resultado importante indicó que la reacción entre el amoníaco y un éter formado por un oxácido mineral daba lugar a la formación de un álcali alcohólico. Clermont también llevó a cabo un extenso programa de investigación acerca del octeno y sus derivados que culminó con la síntesis de un gran número de nuevos derivados, entre ellos, el acetato del óxido de buteno, los haluros y el alcohol caprílico, el octil glicol, la clorhidrina del octil glicol, etc. Clermont determinó la composición del ácido persulfónico, sintetizó la sulfofenil urea y una variedad de tioureas. Estudió una variedad de reacciones del ácido pirúvico, la composición del ácido pirogálico y sintetizó purpúrogalina, y una variedad de sulfuros metálicos, en particular los sulfuros verdes y rosados del manganeso, y la reacción de descomposición del cloruro de amonio con sulfuros metálicos. Asimismo, demostró que la producción de aurina requería la presencia de CO naciente. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y custom: Copyright of Revista CENIC Ciencias Quimicas is the property of Centro Nacional de Investigaciones Cientificas and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. item: Revista CENIC Ciencias Quimicas holder: Centro Nacional de Investigaciones Cientificas dt: @attributes: year: 2022 holdings: @attributes: islocal: N |
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