Application of CRISPR/Cas9 Technology in Cancer Treatment: A Future Direction.
Gene editing, especially with clustered regularly interspaced short palindromic repeats associated protein 9 (CRISPR-Cas9), has advanced gene function science. Gene editing's rapid advancement has increased its medical/clinical value. Due to its great specificity and efficiency, CRISPR/Cas9 can accu...
| Publicado en: | Current Oncology Vol. 30; no. 2; pp. 1954 - 1977 |
|---|---|
| Autores principales: | , , , , , , , , , , , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
MDPI
Feb2023
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=162118306&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 162118306 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 11980052 5EKK jtl: Current Oncology issn: 11980052 maglogo: N pubinfo: dt: Feb2023 vid: 30 iid: 2 pid: 97109 pub: MDPI artinfo: ui: 162118306 10.3390/curroncol30020152 162118306 ppf: 1954 ppct: 23 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Application of CRISPR/Cas9 Technology in Cancer Treatment: A Future Direction. aug: au: Rabaan, Ali A. AlSaihati, Hajir Bukhamsin, Rehab Bakhrebah, Muhammed A. Nassar, Majed S. Alsaleh, Abdulmonem A. Alhashem, Yousef N. Bukhamseen, Ammar Y. Al-Ruhimy, Khalil Alotaibi, Mohammed Alsubki, Roua A. Alahmed, Hejji E. Al-Abdulhadi, Saleh Alhashem, Fatemah A. Alqatari, Ahlam A. Alsayyah, Ahmed Farahat, Ramadan Abdelmoez Abdulal, Rwaa H. Al-Ahmed, Ali H. Imran, Mohd. affil: Molecular Diagnostic Laboratory, Johns Hopkins Aramco Healthcare, Dhahran 31311, Saudi Arabia sug: ab: Gene editing, especially with clustered regularly interspaced short palindromic repeats associated protein 9 (CRISPR-Cas9), has advanced gene function science. Gene editing's rapid advancement has increased its medical/clinical value. Due to its great specificity and efficiency, CRISPR/Cas9 can accurately and swiftly screen the whole genome. This simplifies disease-specific gene therapy. To study tumor origins, development, and metastasis, CRISPR/Cas9 can change genomes. In recent years, tumor treatment research has increasingly employed this method. CRISPR/Cas9 can treat cancer by removing genes or correcting mutations. Numerous preliminary tumor treatment studies have been conducted in relevant fields. CRISPR/Cas9 may treat gene-level tumors. CRISPR/Cas9-based personalized and targeted medicines may shape tumor treatment. This review examines CRISPR/Cas9 for tumor therapy research, which will be helpful in providing references for future studies on the pathogenesis of malignancy and its treatment. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|