Diagnostic Value and Safety of Electromagnetic Navigation Bronchoscopy in Peripheral Pulmonary Lesions: A Meta-analysis.

Background and objective The incidence and mortality of lung cancer have always been at the forefront of malignant tumors. With the development of lung cancer detection techniques, more peripheral pulmonary lesions (PPLs) have been detected. The diagnostic accuracy of procedures for PPLs keeps contr...

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Publicado en:Chinese Journal of Lung Cancer Vol. 26; no. 2; pp. 119 - 135
Autores principales: Xin SUN, Yu SU, Shangyao LI, Yu TIAN, Liang ZHAO
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Chinese Journal of Lung Cancer Feb2023
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: Chinese Journal of Lung Cancer
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      dt: Feb2023
      vid: 26
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      pub: Chinese Journal of Lung Cancer
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        162192585
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        10.3779/j.issn.1009-3419.2023.102.07
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        atl: Diagnostic Value and Safety of Electromagnetic Navigation Bronchoscopy in Peripheral Pulmonary Lesions: A Meta-analysis.
      aug:
        au:
          Xin SUN
          Yu SU
          Shangyao LI
          Yu TIAN
          Liang ZHAO
        affil: National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
      sug:
        subj:
          Electromagnetics
          Bronchoscopy Methods
          Lung Diseases Diagnosis
          Patient Safety
          Human
          Systematic Review
          Meta Analysis
          Embase
          PubMed
          Cochrane Library
          Confidence Intervals
          Odds Ratio
      ab: Background and objective The incidence and mortality of lung cancer have always been at the forefront of malignant tumors. With the development of lung cancer detection techniques, more peripheral pulmonary lesions (PPLs) have been detected. The diagnostic accuracy of procedures for PPLs keeps controversial. This study aims to systematically evaluate the diagnostic value and the safety of electromagnetic navigation bronchoscopy (ENB) in the diagnosis of PPLs. Methods The relevant literatures in the diagnostic yield of PPLs by ENB were systematically retrieved from Wanfang Data Knowledge Service Platform, China National Knowledge Infrastructure, Embase, PubMed, Cochrane Library and Web of Science. The software of Stata 16.0, RevMan 5.4 and Meta-disc 1.4 were used to conduct the meta-analysis. Results A total of 54 literatures with 55 studies were included in our meta-analysis. The pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio and diagnostic odds ratio of ENB in the diagnosis of PPLs were 0.77 (95%CI: 0.73-0.81), 0.97 (95%CI: 0.93-0.99), 24.27 (95%CI: 10.21-57.67), 0.23 (95%CI: 0.19-0.28) and 104.19 (95%CI: 41.85-259.37), respectively. The area under curve (AUC) was 0.90 (95%CI: 0.87-0.92). Meta-regression and subgroup analyses indicated that the potential heterogeneity resulted from study type, additional localization techniques, sample size, lesion size and type of sedation. The use of additional localization techniques and general anesthesia have improved the diagnostic efficiency of ENB in PPLs. The incidence of adverse reactions and complications associated with ENB was very low. Conclusion ENB provides well diagnostic accuracy and safety.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: Chinese
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