Deep Learning–Based Time-to-Death Prediction Model for COVID-19 Patients Using Clinical Data and Chest Radiographs.

Accurate estimation of mortality and time to death at admission for COVID-19 patients is important and several deep learning models have been created for this task. However, there are currently no prognostic models which use end-to-end deep learning to predict time to event for admitted COVID-19 pat...

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Publicado en:Journal of Digital Imaging Vol. 36; no. 1; pp. 178 - 189
Autores principales: Matsumoto, Toshimasa, Walston, Shannon Leigh, Walston, Michael, Kabata, Daijiro, Miki, Yukio, Shiba, Masatsugu, Ueda, Daiju
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: Springer Nature Feb2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2023
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      pub: Springer Nature
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        atl: Deep Learning–Based Time-to-Death Prediction Model for COVID-19 Patients Using Clinical Data and Chest Radiographs.
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        au:
          Matsumoto, Toshimasa
          Walston, Shannon Leigh
          Walston, Michael
          Kabata, Daijiro
          Miki, Yukio
          Shiba, Masatsugu
          Ueda, Daiju
        affil: Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, 545-8585, Osaka, Japan
      sug:
        subj:
          COVID-19 Prognosis
          Death Risk Factors
          Risk Assessment Methods
          Radiography, Thoracic
          Image Processing, Computer Assisted Methods
          Deep Learning
          Prediction Models Evaluation
          Human
          Male
          Female
          Adolescence
          Adult
          Middle Age
          Aged
          Aged, 80 and Over
          Retrospective Design
          Record Review
          Artificial Intelligence
          Cox Proportional Hazards Model
          Neural Networks (Computer)
          Time Factors
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Accurate estimation of mortality and time to death at admission for COVID-19 patients is important and several deep learning models have been created for this task. However, there are currently no prognostic models which use end-to-end deep learning to predict time to event for admitted COVID-19 patients using chest radiographs and clinical data. We retrospectively implemented a new artificial intelligence model combining DeepSurv (a multiple-perceptron implementation of the Cox proportional hazards model) and a convolutional neural network (CNN) using 1356 COVID-19 inpatients. For comparison, we also prepared DeepSurv only with clinical data, DeepSurv only with images (CNNSurv), and Cox proportional hazards models. Clinical data and chest radiographs at admission were used to estimate patient outcome (death or discharge) and duration to the outcome. The Harrel's concordance index (c-index) of the DeepSurv with CNN model was 0.82 (0.75–0.88) and this was significantly higher than the DeepSurv only with clinical data model (c-index = 0.77 (0.69–0.84), p = 0.011), CNNSurv (c-index = 0.70 (0.63–0.79), p = 0.001), and the Cox proportional hazards model (c-index = 0.71 (0.63–0.79), p = 0.001). These results suggest that the time-to-event prognosis model became more accurate when chest radiographs and clinical data were used together.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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