Transfer Learning Approach and Nucleus Segmentation with MedCLNet Colon Cancer Database.

Machine learning has been recently used especially in the medical field. In the diagnosis of serious diseases such as cancer, deep learning techniques can be used to reduce the workload of experts and to produce quick solutions. The nuclei found in the histopathology dataset are an essential paramet...

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Publicado en:Journal of Digital Imaging Vol. 36; no. 1; pp. 306 - 326
Autores principales: Reis, Hatice Catal, Turk, Veysel
Formato: algorithm pictorial research tables/charts Journal Article
Publicado: Springer Nature Feb2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2023
      vid: 36
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-022-00701-z
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        atl: Transfer Learning Approach and Nucleus Segmentation with MedCLNet Colon Cancer Database.
      aug:
        au:
          Reis, Hatice Catal
          Turk, Veysel
        affil: Department of Geomatics Engineering, Gumushane University, 2900, Gumushane, Turkey
      sug:
        subj:
          Machine Learning Utilization
          Cell Nucleus Analysis
          Colorectal Neoplasms Diagnosis
          Deep Learning
          Algorithms
          Diagnostic Imaging
          Histology
          Pretest-Posttest Design
          Human
          Cell Count
          Cell Cycle
          Microscopy
      ab: Machine learning has been recently used especially in the medical field. In the diagnosis of serious diseases such as cancer, deep learning techniques can be used to reduce the workload of experts and to produce quick solutions. The nuclei found in the histopathology dataset are an essential parameter in disease detection. The nucleus segmentation was performed using the colorectal histology MNIST dataset for nucleus detection in this study. The graph theory, PSO, watershed, and random walker algorithms were used for the segmentation process. In addition, we present the 10-class MedCLNet visual dataset consisting of the NCT-CRC-HE-100 K dataset, LC25000 dataset, and GlaS dataset that can be used in transfer learning studies from deep learning techniques. The study proposes a transfer learning technique using the MedCLNet database. Deep neural networks pre-trained with the proposed transfer learning method were used in the classification with the colorectal histology MNIST dataset in the experimental process. DenseNet201, DenseNet169, InceptionResNetV2, InceptionV3, ResNet152V2, ResNet101V2, and Xception deep learning algorithms were used in transfer learning and the classification studies. The proposed approach was analyzed before and after transfer learning with different methods (DenseNet169 + SVM, DenseNet169 + GRU). In the performance measurement, using the colorectal histology MNIST dataset, 94.29% accuracy was obtained in the DenseNet169 model, which was initiated with random weights in the multi-classification study, and 95.00% accuracy after transfer learning was applied. In comparison with the results obtained from empirical studies, it was demonstrated that the proposed method produced satisfactory outcomes. The application is expected to provide a secondary evaluation for physicians in colon cancer detection and the segmentation.
      pubtype: Academic Journal
      doctype:
        algorithm
        pictorial
        research
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      ougenre: Article
    language: English
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