Pros and Cons of Breath Testing for Small Intestinal Bacterial Overgrowth and Intestinal Methanogen Overgrowth.

Breath testing is the most widely utilized modality to diagnose small intestinal bacterial overgrowth (SIBO) and/or intestinal methanogen overgrowth (IMO). Although SIBO can be diagnosed with small bowel aspiration and breath testing, IMO can only be diagnosed with breath testing in clinical practic...

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Publicado en:Gastroenterology & Hepatology Vol. 19; no. 3; pp. 140 - 147
Autores principales: Lim, Jane, Rezaie, Ali
Formato: review tables/charts Journal Article
Publicado: Gastro-Hep Communications, Inc Mar2023
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Gastro-Hep Communications, Inc
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        atl: Pros and Cons of Breath Testing for Small Intestinal Bacterial Overgrowth and Intestinal Methanogen Overgrowth.
      aug:
        au:
          Lim, Jane
          Rezaie, Ali
        affil: GI Motility Program, Karsh Division of Gastroenterology and Hepatology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California
      sug:
        subj:
          Malabsorption Syndromes Diagnosis
          Breath Tests Methods
          Intestine, Small Microbiology
          Bacterial Infections Diagnosis
          Diagnosis, Digestive System Methods
          Predictive Value of Tests
          Sensitivity and Specificity
      ab: Breath testing is the most widely utilized modality to diagnose small intestinal bacterial overgrowth (SIBO) and/or intestinal methanogen overgrowth (IMO). Although SIBO can be diagnosed with small bowel aspiration and breath testing, IMO can only be diagnosed with breath testing in clinical practice. Breath testing can tailor antibiotic therapy and predict response to treatment; however, the test is limited by its indirect method of measurement and concerns about the variability of orocecal transit time. Like any clinical test, breath testing has inherent strengths and limitations, and results must be interpreted with consideration of the clinical context and influencing factors. Recent studies have demonstrated the expanding clinical utility of breath testing in the diagnosis, management, and prediction of treatment response in SIBO and particularly in IMO along with the identification of distinct breath test patterns such as flat-line and high baseline hydrogen. This article reviews the strengths and limitations of breath testing in diagnosing SIBO and IMO as well as its expanding utility in clinical practice.
      pubtype: Academic Journal
      doctype:
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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