Efficacy and safety of twice‐daily tramadol hydrochloride bilayer sustained‐release tablets with an immediate release component for postherpetic neuralgia: Results of a Phase III, randomized, double‐blind, placebo‐controlled, treatment‐withdrawal study

Background: We investigated the efficacy and safety of twice‐daily bilayer sustained‐release tramadol hydrochloride tablets (35% immediate‐release; 65% sustained‐release) in patients with postherpetic neuralgia. Methods: This was a Phase III treatment‐withdrawal study with 1–4‐week dose‐escalation,...

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Publicado en:Pain Practice Vol. 23; no. 3; pp. 277 - 290
Autores principales: Kawai, Shinichi, Hasegawa, Jun, Ito, Hideki, Fukuuchi, Yasuo, Nakano, Hideshi, Ohtani, Hideaki, Sasaki, Kazutaka, Adachi, Takeshi
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: Wiley-Blackwell Mar2023
Acceso en línea:Ver este registro en EBSCOhost