Exploring the Impact of Tensions in Stakeholder Norms on Designing for Value Change: The Case of Biosafety in Industrial Biotechnology.
Synthetic biologists design and engineer organisms for a better and more sustainable future. While the manifold prospects are encouraging, concerns about the uncertain risks of genome editing affect public opinion as well as local regulations. As a consequence, biosafety and associated concepts, suc...
| Publicado en: | Science & Engineering Ethics Vol. 29; no. 2; pp. 1 - 29 |
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| Autores principales: | , , , |
| Formato: | Artículo |
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Springer Nature
Apr2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=hlh&AN=162283548&site=ehost-live header: @attributes: shortDbName: hlh uiTerm: 162283548 longDbName: Humanities International Complete uiTag: AN controlInfo: bkinfo: jinfo: jid: 13533452 GNI jtl: Science & Engineering Ethics issn: 13533452 maglogo: N pubinfo: dt: Apr2023 vid: 29 iid: 2 pid: 237 pub: Springer Nature artinfo: ui: 162283548 10.1007/s11948-023-00432-6 ppf: 1 ppct: 28 formats: fmt: – @attributes: type: T – @attributes: type: P size: 2.1MB tig: atl: Exploring the Impact of Tensions in Stakeholder Norms on Designing for Value Change: The Case of Biosafety in Industrial Biotechnology. aug: au: Asin-Garcia, Enrique Robaey, Zoë Kampers, Linde F. C. Martins dos Santos, Vitor A. P. affil: Laboratory of Systems and Synthetic Biology, Wageningen University & Research, 6708, Wageningen, WE, The Netherlands Bioprocess Engineering Group, Wageningen University & Research, 6700, Wageningen, AA, The Netherlands Department of Social Sciences, Wageningen University & Research, 6708, Wageningen, WE, The Netherlands LifeGlimmer GmbH, Berlin, Germany sug: keyword: Biosafety Genetic safeguards Industrial biotechnology Multistakeholder approach Safe-by-design framework Value sensitive design ab: Synthetic biologists design and engineer organisms for a better and more sustainable future. While the manifold prospects are encouraging, concerns about the uncertain risks of genome editing affect public opinion as well as local regulations. As a consequence, biosafety and associated concepts, such as the Safe-by-design framework and genetic safeguard technologies, have gained notoriety and occupy a central position in the conversation about genetically modified organisms. Yet, as regulatory interest and academic research in genetic safeguard technologies advance, the implementation in industrial biotechnology, a sector that is already employing engineered microorganisms, lags behind. The main goal of this work is to explore the utilization of genetic safeguard technologies for designing biosafety in industrial biotechnology. Based on our results, we posit that biosafety is a case of a changing value, by means of further specification of how to realize biosafety. Our investigation is inspired by the Value Sensitive Design framework, to investigate scientific and technological choices in their appropriate social context. Our findings discuss stakeholder norms for biosafety, reasonings about genetic safeguards, and how these impact the practice of designing for biosafety. We show that tensions between stakeholders occur at the level of norms, and that prior stakeholder alignment is crucial for value specification to happen in practice. Finally, we elaborate in different reasonings about genetic safeguards for biosafety and conclude that, in absence of a common multi-stakeholder effort, the differences in informal biosafety norms and the disparity in biosafety thinking could end up leading to design requirements for compliance instead of for safety. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y custom: Science & Engineering Ethics is a copyright of Springer, 2023. All Rights Reserved. item: Science & Engineering Ethics holder: Springer Nature dt: @attributes: year: 2023 holdings: @attributes: islocal: N |
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