Acoustic Measures of Dysphonia in Amyotrophic Lateral Sclerosis.
Purpose: Identifying efficacious measures to characterize dysphonia in complex neurodegenerative diseases is key to optimal assessment and intervention. This study evaluates the validity and sensitivity of acoustic features of phonatory disruption in amyotrophic lateral sclerosis (ALS). Method: Fort...
| Publicado en: | Journal of Speech, Language & Hearing Research Vol. 66; no. 3; pp. 872 - 888 |
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| Autores principales: | , , , , , , , , , |
| Formato: | Artículo |
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American Speech-Language-Hearing Association
Mar2023
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=162305538&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 162305538 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 10924388 1SM jtl: Journal of Speech, Language & Hearing Research issn: 10924388 maglogo: N pubinfo: dt: Mar2023 vid: 66 iid: 3 pid: 42 pub: American Speech-Language-Hearing Association artinfo: ui: 162305538 10.1044/2022_JSLHR-22-00363 ppf: 872 ppct: 16 formats: fmt: @attributes: type: P size: 847KB tig: atl: Acoustic Measures of Dysphonia in Amyotrophic Lateral Sclerosis. aug: au: Maffei, Marc F. Green, Jordan R. Murton, Olivia Yunusova, Yana Rowe, Hannah P. Wehbe, Farah Diana, Kathleen Nicholson, Katharine Berry, James D. Connaghan, Kathryn P. affil: Department of Communication Sciences and Disorders, MGH Institute of Health Professions, Boston, MA Speech and Hearing Bioscience and Technology Program, Harvard University, Cambridge, MA Department of Speech-Language Pathology, University of Toronto, Ontario, Canada Hurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, Ontario, Canada Toronto Rehabilitation Institute, University Health Network, Ontario, Canada Department of Neurology, Neurological Clinical Research Institute, Massachusetts General Hospital, Boston su: Physiological aspects of speech Amyotrophic lateral sclerosis Descriptive statistics Voice disorders sug: subj: Physiological aspects of speech Amyotrophic lateral sclerosis Descriptive statistics Voice disorders ab: Purpose: Identifying efficacious measures to characterize dysphonia in complex neurodegenerative diseases is key to optimal assessment and intervention. This study evaluates the validity and sensitivity of acoustic features of phonatory disruption in amyotrophic lateral sclerosis (ALS). Method: Forty-nine individuals with ALS (40-79 years old) were audio-recorded while producing a sustained vowel and continuous speech. Perturbation/noisebased (jitter, shimmer, and harmonics-to-noise ratio) and cepstral/spectral (cepstral peak prominence, low-high spectral ratio, and related features) acoustic measures were extracted. The criterion validity of each measure was assessed using correlations with perceptual voice ratings provided by three speech-language pathologists. Diagnostic accuracy of the acoustic features was evaluated using area-under-the-curve analysis. Results: Perturbation/noise-based and cepstral/spectral features extracted from/a/were significantly correlated with listener ratings of roughness, breathiness, strain, and overall dysphonia. Fewer and smaller correlations between cepstral/spectral measures and perceptual ratings were observed for the continuous speech task, although post hoc analyses revealed stronger correlations in speakers with less perceptually impaired speech. Area-under-the-curve analyses revealed that multiple acoustic features, particularly from the sustained vowel task, adequately differentiated between individuals with ALS with and without perceptually dysphonic voices. Conclusions: Our findings support using both perturbation/noise-based and cepstral/spectral measures of sustained/a/to assess phonatory quality in ALS. Results from the continuous speech task suggest that multisubsystem involvement impacts cepstral/spectral analyses in complex motor speech disorders such as ALS. Further investigation of the validity and sensitivity of cepstral/spectral measures during continuous speech in ALS is warranted. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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