Prospective Validation of 2B-Cool : Integrating Wearables and Individualized Predictive Analytics to Reduce Heat Injuries.

Introduction: An uncontrollably rising core body temperature (TC) is an indicator of an impending exertional heat illness. However, measuring TC invasively in field settings is challenging. By contrast, wearable sensors combined with machine-learning algorithms can continuously monitor TC nonintrusi...

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Publicado en:Medicine & Science in Sports & Exercise Vol. 55; no. 4; pp. 751 - 765
Autores principales: LAXMINARAYAN, SRINIVAS, HORNBY, SAMANTHA, BELVAL, LUKE N., GIERSCH, GABRIELLE E. W., MORRISSEY, MARGARET C., CASA, DOUGLAS J., REIFMAN, JAQUES
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: Lippincott Williams & Wilkins Apr2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2023
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      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
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        atl: Prospective Validation of 2B-Cool : Integrating Wearables and Individualized Predictive Analytics to Reduce Heat Injuries.
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          LAXMINARAYAN, SRINIVAS
          HORNBY, SAMANTHA
          BELVAL, LUKE N.
          GIERSCH, GABRIELLE E. W.
          MORRISSEY, MARGARET C.
          CASA, DOUGLAS J.
          REIFMAN, JAQUES
        affil: Department of Defense Biotechnology High Performance Computing Software Applications Institute, Telemedicine and Advanced Technology Research Center, U.S. Army Medical Research and Development Command, Fort Detrick, MD
      sug:
        subj:
          Wearable Sensors Equipment and Supplies
          Smartphone
          Machine Learning
          Heat Stress Disorders Prevention and Control
          Body Temperature
          Sensitivity and Specificity
          Human
          Male
          Female
          Descriptive Statistics
          Comparative Studies
          Prediction Models
          Crossover Design
          Treadmills
          Algorithms
          Environment, Controlled
          Randomized Controlled Trials
          Adolescence
          Young Adult
          Vital Signs
          Heart Rate
          Adolescent: 13-18 years
          Male
          Female
      ab: Introduction: An uncontrollably rising core body temperature (TC) is an indicator of an impending exertional heat illness. However, measuring TC invasively in field settings is challenging. By contrast, wearable sensors combined with machine-learning algorithms can continuously monitor TC nonintrusively. Here, we prospectively validated 2B-Cool , a hardware/software system that automatically learns how individuals respond to heat stress and provides individualized estimates of TC, 20-min ahead predictions, and early warning of a rising TC. Methods: We performed a crossover heat stress study in an environmental chamber, involving 11 men and 11 women (mean ± SD age = 20 ± 2 yr) who performed three bouts of varying physical activities on a treadmill over a 7.5-h trial, each under four different clothing and environmental conditions. Subjects wore the 2B-Cool system, consisting of a smartwatch, which collected vital signs, and a paired smartphone, which housed machine-learning algorithms and used the vital sign data to make individualized real-time forecasts. Subjects also wore a chest strap heart rate sensor and a rectal probe for comparison purposes. Results: We observed very good agreement between the 2B-Cool forecasts and the measured TC, with a mean bias of 0.16°C for TC estimates and nearly 75% of measurements falling within the 95% prediction intervals of ±0.62°C for the 20-min predictions. The early-warning system results for a 38.50°C threshold yielded a 98% sensitivity, an 81% specificity, a prediction horizon of 35 min, and a false alarm rate of 0.12 events per hour. We observed no sex differences in the measured or predicted peak TC. Conclusion: 2B-Cool provides early warning of a rising TC with a sufficient lead time to enable clinical interventions and to help reduce the risk of exertional heat illness.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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